共查询到20条相似文献,搜索用时 29 毫秒
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G. Zbinden 《Die Naturwissenschaften》1982,69(6):255-259
The paper reviews current concepts of toxicological evaluation of new drugs and other chemicals. Instead of completing a predetermined check-list toxicologists now consider the potential adverse effects of the substances under actual conditions of use. They then design experimental models which have a high probability to predict the toxic effects. Moreover, the enhanced susceptibilities of special risk populations is more and more taken into consideration. 相似文献
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为阻止或减缓嗜酸性硫氧化菌对硫化矿物的氧化,研究了十二烷基磺酸钠(SDS)对广东韶关大宝山多金属尾矿区分离出的氧化亚铁硫杆菌的杀菌效果.为提高抑菌剂的有效利用率,采用滴制法将其制备成具有缓释功能的抑菌剂滴丸,并分析了抑菌剂滴丸的表面特征、元素组成及缓释性能.结果发现:滴制法可以把SDS均匀地分散在以醋酸纤维素为骨架的缓释滴丸内部;滴丸的载药率可以达到40%以上;实验周期内杀菌成分可在酸性溶液中持续缓慢溶出,溶液中ρ(SDS)逐渐升高.氧化亚铁硫杆菌摇瓶浸矿结果显示:使用抑菌剂缓释滴丸后,实验周期内溶液的pH值、Eh变化幅度较小,而且Zn2+、总Fe的溶出率分别比未加滴丸的处理低61.37%、84.44%,缓释杀菌作用显著. 相似文献
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Liesbeth Vossaert Imen Chakchouk Roni Zemet Ignatia B. Van den Veyver 《黑龙江环境通报》2021,41(10):1202-1214
Investigators have long been interested in the natural phenomenon of fetal and placental cell trafficking into the maternal circulation. The scarcity of these circulating cells makes their detection and isolation technically challenging. However, as a DNA source of fetal origin not mixed with maternal DNA, they have the potential of considerable benefit over circulating cell-free DNA-based noninvasive prenatal genetic testing (NIPT). Endocervical trophoblasts, which are less rare but more challenging to recover are also being investigated as an approach for cell-based NIPT. We review published studies from around the world describing both forms of cell-based NIPT and highlight the different approaches’ advantages and drawbacks. We also offer guidance for developing a sound cell-based NIPT protocol. 相似文献
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在LabWindows/CVI环境下,提出了基于PCDAQmx数据采集卡(6014)的伺服阀测试系统实现的原理与方法,并研究了伺服阀参数指标的算法.重点介绍了关键功能实现的方法,如流量特性曲线的测量及拟合算法、实现频率特性测试的关键技术及算法以及硬件接线自动控制的实现方法. 相似文献
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Prenatal paternity testing was evaluated by DNA analysis in chorionic villus biopsies obtained during the 7th-22nd weeks of gestation. Using highly polymorphic variable number of tandem repeats (VNTR) probes, we analysed four cases consisting of mother/child/alleged father trios. In all cases, we were able to detect maternal and paternal alleles and could establish or exclude paternity. The application of DNA analysis represents a new important diagnostic aid for all cases that require a prenatal identification of paternity. 相似文献
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本文针对56个海洋行业监测检测实验室进行的海洋生物体中As和海洋沉积物中Cd含量测定结果,采用稳健统计技术(Robust statistical technique)方法进行了评价分析。结果表明,参加本次能力验证活动的大多数实验室检测能力良好,其出具的检测数据可信。少数实验室检测结果有问题或不满意,鼓励这些实验室认真查找问题,积极采取纠正措施,改进实验室管理和质量控制,提升并保持检测能力。研究表明,稳健统计技术在本次实验室能力验证结果评价中应用效果良好,真实全面的反应了各实验室检测能力现状。 相似文献