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We report the diagnosis of amnion rupture sequence made by sonography and fetoscopy during the first trimester of gestation in a case of missed abortion. The investigation revealed a demised fetus with the characteristics of 9 weeks of development. The early fetus had an amnion adhesion at the tip of the nose and strands of amnion wrapped around the terminal phalanges of both feet. No defects in addition to the face and limb involvement were identified. The karyotype was normal: 46,XX. In the reported case, fetoscopy allowed confirmation of the sonographic diagnosis of an amnion rupture sequence in the first trimester of gestation and consequently helped to clarify the cause of abortion in this case of early fetal demise. Copyright © 2001 John Wiley & Sons, Ltd. 相似文献
94.
Staffan Jacob Léa Colmas Nathalie Parthuisot Philipp Heeb 《Die Naturwissenschaften》2014,101(11):929-938
Parasites are known to exert selective pressures on host life history traits since the energy and nutrients needed to mount an immune response are no longer available to invest in other functions. Bird feathers harbour numerous microorganisms, some of which are able to degrade feather keratin (keratinolytic microorganisms) and affect feather integrity and colouration in vitro. Although named “feather-degrading” microorganisms, experimental evidence for their effects on feathers of free-living birds is still lacking. Here, we tested whether (i) keratinolytic microorganisms can degrade feathers in vivo and thus modify the colour of feathers during the nesting period and (ii) whether feather microorganisms have a long-term effect on the investment in colouration of newly moulted feathers. We designed treatments to either favour or inhibit bacterial growth, thus experimentally modifying plumage bacterial communities, in a wild breeding population of great tits (Parus major). Our analyses revealed no significant effects of the treatments on feather colours. Moreover, we found that differences in bacterial exposure during nesting did not significantly affect the colouration of newly moulted feathers. Our results suggest that significant feather degradation obtained during in vitro studies could have led to an overestimation of the potential of keratinolytic microorganisms to shape feather colouration in free-living birds. 相似文献
95.
Yulong Wang Zhonghao Bai Libo Cao Matthew P. Reed Kurt Fischer Angelo Adler 《Traffic injury prevention》2015,16(4):S75-S83
Objective: Recent field data analyses have shown that the safety advantages of rear seats relative to the front seats have decreased in newer vehicles. Separately, the risks of certain injuries have been found to be higher for obese occupants. The objective of this study is to investigate the effects of advanced belt features on the protection of rear-seat occupants with a range of body mass index (BMI) in frontal crashes.Methods: Whole-body finite element human models with 4 BMI levels (25, 30, 35, and 40 kg/m2) developed previously were used in this study. A total of 52 frontal crash simulations were conducted, including 4 simulations with a standard rear-seat, 3-point belt and 48 simulations with advanced belt features. The parameters varied in the simulations included BMI, load limit, anchor pretensioner, and lap belt routing relative to the pelvis. The injury measurements analyzed in this study included head and hip excursions, normalized chest deflection, and torso angle (defined as the angle between the hip–shoulder line and the vertical direction). Analyses of covariance were used to test the significance (P <.05) of the results.Results: Higher BMI was associated with greater head and hip excursions and larger normalized chest deflection. Higher belt routing increased the hip excursion and torso angle, which indicates a higher submarining risk, whereas the anchor pretensioner reduced hip excursion and torso angle. Lower load limits decreased the normalized chest deflection but increased the head excursion. Normalized chest deflection had a positive correlation with maximum torso angle. Occupants with higher BMI have to use higher load limits to reach head excursions similar to those in lower BMI occupants.Discussion and Conclusion: The simulation results suggest that optimizing load limiter and adding pretensioner(s) can reduce injury risks associated with obesity, but conflicting effects on head and chest injuries were observed. This study demonstrated the feasibility and importance of using human models to investigate protection for occupants with various BMI levels. A seat belt system capable of adapting to occupant size and body shape will improve protection for obese occupants in rear seats. 相似文献
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Stanley O. Agbo Markku Keinänen Sarita Keski-Saari Juha Lemmetyinen Jarkko Akkanen Matti T. Leppänen Philipp Mayer Jussi V.K. Kukkonen 《Chemosphere》2013
The regulation of endogenous metabolites is still not fully understood in aquatic invertebrates exposed concurrently to toxicants and hypoxia. Despite the prevalence of hypoxia in the aquatic environment, toxicity estimations seldom account for multiple stressors thereby differing from natural conditions. In this study, we examined the influence of hypoxia (<30% O2) on contaminant uptake and the composition of intracellular metabolites in Lumbriculus variegatus exposed to benzo(a)pyrene (B(a)P, 3 μg L−1), chlorpyrifos (CPF, 100 μg L−1) or pentachlorophenol (PCP, 100 μg L−1). Tissue extracts of worms were analyzed for 123 metabolites by gas chromatography–mass spectrometry and metabolite levels were then related to treatments and exposure time. Hypoxia markedly increased the accumulation of B(a)P and CPF, which underlines the significance of oxygen in chemical uptake. The oxygen effect on PCP uptake was less pronounced. Succinate and glycerol-3-phosphate increased significantly (p < 0.0001) following hypoxic treatment, whereas sugars, cysteine, and cholesterol were effectively repressed. The buildup of succinate coupled with the corresponding decline in intracellular 2-oxo- and 2-hydroxy glutaric acid is indicative of an active hypoxia inducible factor mechanism. Glutamate, and TCA cycle intermediates (fumarate, and malate) were disturbed and evident in their marked suppression in worms exposed concurrently to hypoxia and PCP. Clearly, hypoxia was the dominant stressor for individuals exposed to B(a)P or CPF, but to a lesser extent upon PCP treatment. And since oxygen deprivation promotes the accumulation of different toxicants, there may be consequences on species composition of metabolites in natural conditions. 相似文献
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Poultry litter applications to land have been based on crop N requirements, resulting in application of P in excess of plant requirements, which may cause degradation of water quality in the Chesapeake Bay watershed. The effect of litter source (the Delmarva Peninsula and Moorefield, West Virginia) and composting of poultry litter on N mineralization and availability of P in two soil types (sandy loam and silt loam) was determined in a controlled environment for 120 d. Nitrogen mineralization (percent total organic N converted to inorganic nitrogen) rates were higher for fresh litter (range of 42 to 64%) than composted litter (range of 1 to 9%). The N mineralization rate of fresh litter from the Delmarva Peninsula was consistently lower than the fresh litter from Moorefield, WV. The N mineralization rate of composted litter from either source was not significantly different for each soil type (7 to 9% in sandy loam and 1 to 5% in silt loam) even though composting conditions were completely different at the two composting facilities. Litter source had a large effect on N mineralization rates of fresh but not composted poultry litter. Composting yielded a more predictable and reliable source of mineralizable N than fresh litter. Water-extractable phosphorus (WEP) was similar in soils amended with composted litter from WV and fresh litter from both sources (approximately 10 to 25 and 2 to 14 mg P kg(-1) for sandy loam and silt loam, respectively). Mehlich 1-extractable phosphorus (MEP) was similar in soils amended with WV fresh litter and composted litter from both sources (approximately 100 to 140 and 60 to 90 mg P kg(-1) for sandy loam and silt loam, respectively). These results suggest that the composting process did not consistently reduce WEP and MEP, and P can be as available in composted poultry litter as in fresh poultry litter. 相似文献
100.
Paul S. Adler 《组织行为杂志》1991,12(5):447-460
This paper presents and compares case studies of three Flexible Manufacturing Systems (FMSs). Interviews, observation and questionnaire data from two installations are compared to data presented in previous studies of a third installation. Whereas the previous research found that FMS workers suffered from a lack of autonomy and control, this does not characterize work on the two new installations. While in one of the new cases, the difference may have been due to its semi-autonomous team organization, the other new installation was organized along rather conventional lines. Despite its conventional organization, workers in this latter FMS expressed high levels of satisfaction and motivation and their system operated at a very high level of efficiency. This result suggests that future research might fruitfully reconsider whether the relevant factor of satisfaction and motivation is autonomy or efficacy. 相似文献