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41.
Dana B. Shealy Michael A. Bonin Joe V. Wooten David L. Ashley Larry L. Needham Andrew E. Bond 《Environment international》1996,22(6):661-675
As the annual use of pesticides in the United States has escalated, public health agencies have become increasingly concerned about chronic pesticide exposure. However, without reliable, accurate analytical methods for biological monitoring, low-level chronic exposures are often difficult to assess. A method for measuring simultaneously the urinary residues of as many as 20 pesticides has been significantly improved. The method uses a sample preparation which includes enzyme digestion, extraction, and chemical derivatization of the analytes. The derivatized analytes are measured by using gas chromatography coupled with isotope-dilution tandem mass spectrometry. The limits of detection of the modified method are in the high pg/L - low μg/L range, and the average coefficient of variation (CV) of the method was below 20% for most analytes, with approximately 100% accuracy in quantification. This method was used to measure the internal doses of pesticides among selected farmer applicators and their families. Definite exposure and elimination patterns (i.e., an increase in urinary analyte levels following application and then a gradual decrease to background levels) were observed among the farmer applicators and many of the family members whose crops were treated with carbaryl, dicamba, and 2,4-D esters and amines. Although the spouses of farm workers sometimes exhibited the same elimination pattern, the levels of the targeted pesticides or metabolites found in their urine were not outside the ranges found in the general U.S. population (reference range). The farmer applicators who applied the pesticides and some of their children appeared to have higher pesticide or metabolite levels in their urine than those found in the general U.S. population, but their levels were generally comparable to or lower than reported levels in other occupationally exposed individuals. These results, however, were obtained from a nonrandom sampling of farm residents specifically targeted to particular exposures who may have altered their practices because they were being observed; therefore, further study is required to determine if these results are representative of pesticide levels among residents on all farms where these pesticides are applied using the same application techniques. Using this method to measure exposure in a small nonrandom farm population allowed differentiation between overt and background exposure. In addition, the important role of reference-range information in distinguishing between various levels of environmental exposure was reaffirmed. 相似文献
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The prevalence of communicable diseases in the English speaking Caribbean has declined considerably over the last two decades, creating a false sense of security and complacency in implementing continuous preventive measures such as immunization.
Poliomyelitis is one such case in paint. The last case of paralytic poliomyelitis was reported in Jamaica in 1969. Then twelve years later, in May 1982, the Ministry of Health announced the outbreak of poliomyelitis in the parish of St. James, caused by the Type I virus.
This paper traces the history of epidemics of poliomyelitis in Jamaica from 1954 to 1982, the Government's policies and strategies for immunization and demonstrates that preventive intervention through immunization is cheaper and preferable to crisis management caused by epidemics. The evaluation of the social and economic costs of the 1982 poliomyelitis epidemic in Jamaica provides conclusive evidence in support of preventive intervention. 相似文献
Poliomyelitis is one such case in paint. The last case of paralytic poliomyelitis was reported in Jamaica in 1969. Then twelve years later, in May 1982, the Ministry of Health announced the outbreak of poliomyelitis in the parish of St. James, caused by the Type I virus.
This paper traces the history of epidemics of poliomyelitis in Jamaica from 1954 to 1982, the Government's policies and strategies for immunization and demonstrates that preventive intervention through immunization is cheaper and preferable to crisis management caused by epidemics. The evaluation of the social and economic costs of the 1982 poliomyelitis epidemic in Jamaica provides conclusive evidence in support of preventive intervention. 相似文献
43.
Motallebi N Taylor CA Turkiewicz K Croes BE 《Journal of the Air & Waste Management Association (1995)》2003,53(12):1509-1516
It will be many years before the recently deployed network of fine particulate matter with an aerodynamic diameter less than 2.5 microm (PM2.5) Federal Reference Method (FRM) samplers produces information on nonattainment areas, trends, and source impacts. However, data on PM2.5 and its major constituents have been routinely collected in California for the past 20 years. The California Air Resources Board operated as many as 20 dichotomous (dichot) samplers for PM2.5 and coarse PM (PM10-2.5). The California Acid Deposition Monitoring Program (CADMP) collected 12-h-average PM2.5 and PM10 from 1988 to 1995 at ten urban and rural sites and 24-h-average PM2.5 at five urban sites since 1995. Beginning in 1994, the Children's Health Study collected 2-week averages of PM2.5 in 12 communities in southern California using the Two-Week Sampler (TWS). Comparisons of collocated samples establish relationships between the dichot, CADMP, and TWS samplers and the 82-site network of PM2.5 FRM samplers deployed since 1999 in California. PM mass data from the different monitoring programs have modest to high correlation to FRM mass data, fairly small systematic biases and negative proportional biases ranging from 7 to 22%. If the biases are taken into account, all of the programs should be considered comparable with the FRM program. Thus, historical data can be used to develop long-term PM trends in California. 相似文献
44.
Elizabeth R. Mathews Jennifer L. Woo Dean Phillips Nathan Billington Dean Barnett Ashley E. Franks 《环境科学学报(英文版)》2020,32(1):133-148
Controlling hydrogen sulfide (H2S) odors and emissions using a single, effective treatment across a town-scale sewer network is a challenge faced by many water utilities. Implementation of a sewer diversion provided the opportunity to compare the effectiveness of magnesium hydroxide (Mg(OH)2) and two biological dosing compounds (Bioproducts A and B), with different modes of action (MOA), in a field-test across a large sewer network. Mg(OH)2 increases sewer pH allowing suppression of H2S release into the sewer environment while Bioproduct A acts to disrupt microbial communication through quorum sensing (QS), reducing biofilm integrity. Bioproduct B reduces H2S odors by scouring the sewer of fats, oils and grease (FOGs), which provide adhesion points for the microbial biofilm. Results revealed that only Mg(OH)2 altered the microbial community structure and reduced H2S emissions in a live sewer system, whilst Bioproducts A and B did not reduce H2S emissions or have an observable effect on the composition of the microbial community at the dosed site. Study results recommend in situ testing of dosing treatments before implementation across an operational system. 相似文献
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Ashley Dodsworth 《环境政策》2016,25(2):391-393
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Using self‐determination theory to understand the relationship between calling enactment and daily well‐being
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This paper contributes to the calling literature by using self‐determination theory—a theory that makes distinctions between different types of motivation—in order to gain a better understanding of how enacting a calling may relate both positively and negatively to well‐being. We use a daily diary method novel to the calling field and a sample with a distinctive calling, Church of England clergy. We expect daily calling enactment to relate positively to daily well‐being via more autonomous forms of motivation (intrinsic and identified motivation) and negatively via less autonomous forms (introjected motivation). Furthermore, we consider how the relationship between calling enactment and motivation may be moderated by perceived competence. The hypotheses were tested using multi‐level structural equation modeling. There was strong support for calling enactment relating positively to well‐being, and this relationship was fully mediated by intrinsic and identified motivation; the hypothesized negative pathway, from calling enactment, to introjected motivation, to well‐being, was not supported. However, perceived competence was found to moderate some of the relationships between calling and the motivation types, where calling enactment is linked to lower introjected motivation at high levels of competence. Copyright © 2015 John Wiley & Sons, Ltd. 相似文献
50.
<正>Introduction Cadmium is considered a human carcinogen by the International Agency for Research on Cancer(IARC,1993)and the US National Toxicology Program(NTP,1997).Cadmium contamination of food crops is a persistent issue for both the agricultural industry as well as consumers.This is an issue for agriculture because cadmium can be present in soils naturally or as a result of industrial processes and can contaminate foods that are consumed by humans.Industrial 相似文献