Prenatal diagnosis of Fanconi anemia (Group C) subsequent to abnormal sonographic findings

Manifestations of Fanconi Anemia Complementation Group C (FA-C) include multiple major congenital malformations, hypoplastic radius, absent thumb, growth retardation, elfin-like facial features, microphthalmia, microcephaly, café-au-lait spots, early onset of hematologic disease and poor survival (Auerbach, 1997). We describe two cases in which second-trimester sonographic findings led to parental carrier testing for FA-C and subsequent prenatal diagnosis of affected fetuses. Copyright © 2005 John Wiley & Sons, Ltd.     

Strengthening the link between climate change adaptation and national development plans: lessons from the case of population in National Adaptation Programmes of Action (NAPAs)

As climate change adaptation planning moves beyond short term National Adaptation Programmes of Action (NAPA) to longer-term approaches, it is instructive to review the NAPA process and examine how well it was linked to national development planning. This paper reviews 41 NAPAs submitted by Least Developed Countries (LDCs) to the United Nations Framework Convention on Climate Change (UNFCCC), to assess the NAPA process in terms of NAPAs integration with countries’ national development strategies. The review outlines the actors involved in developing NAPAs and identifies the range of interventions included in countries’ priority adaptation actions. The paper uses the example of population as an issue related to both climate change and national development to assess how it is addressed as part of LDCs’ adaptation and national development agendas. The analysis shows that although countries recognize population pressure as an issue related to the ability to cope with climate change and as a factor hindering progress in meeting development goals, it is not well incorporated into either adaptation planning or in national development strategies. Among the 41 NAPAs, 37 link high and rapid population growth to climate change. Moreover, six NAPAs clearly state that slowing population growth or investments in reproductive health/family planning (RH/FP) should be considered among the country’s priority adaptation actions. Furthermore, two NAPAs actually propose a project with components of RH/FP among their priority adaptation interventions, although none of them has yet been funded. The paper points to structural issues that hamper better alignment between climate change adaptation and national development planning and offers recommendations for longer-term adaptation strategies that better meet the development needs of countries.     

Ferulic acid supplementation for 40 days in hair ewe lambs experiencing seasonal heat stress: short-term effects on physiological responses,growth, metabolism,and hematological profile

Environmental Science and Pollution Research - Free ferulic acid (FA) is a natural compound with antioxidant properties which mitigates the negative effects of cold stress in sheep; however, its...     

A simulator study of driving behavior and mental workload in mixed-use arterial road environments

Objectives: Mixed-use urban environments, such as arterial roads with adjacent commercial land uses, represent crash locations with the highest risk. These locations are often characterized by high volumes of motor vehicle traffic, on-street parking, and interactions with multiple road user groups such as pedestrians, cyclists, and public transportation. The objective of this study was to investigate previously identified crash risk factors for mixed-use urban environments and assess how parking occupancy, center medians, and cyclist volume influence performance and workload in a driving simulator study.

Methods: Thirty participants were recruited for the study. Participants completed 6 drives that presented different combinations of cyclist volume, median condition, and parking occupancy. Incorporated into the simulator drives was a secondary peripheral detection task (PDT) designed to measure mental workload. Participants provided subjective assessments of workload using the Rating Scale Mental Effort (RSME).

Results: Mean lateral lane position was found to significantly vary across the 3 independent variables of parking occupancy, cyclist volume, and median conditions. No significant changes were identified for mean speed across the conditions. Subjective and objective measures of workload identified changes due to the presence of cyclists with slower reaction times for the PDT task when cyclists were present.

Conclusion: The findings provide insight into the interaction of road design elements in mixed-use urban road environments and demonstrate that increasingly complex environments increase driver demand. This has important road design implications for mixed-use arterial roads, which are often characterized by complex interactions between multiple road user groups.     

Respiratory health assessment and exposure to polycyclic aromatic hydrocarbons in Mexican indigenous population

Environmental Science and Pollution Research - Indoor air pollution is an important risk factor for the generation of lung diseases in developing countries. The indigenous population is...     

History of atmospheric environment

There have been great transitions in the science of air pollution and science publishing since the journal began as the International Journal of Air Pollution in 1958. Atmospheric Environment witnessed the increased understanding of smog photochemistry in the late 1950s and the emerging fears of ozone depletion in the 1970s. The journal has grown, but not without the need to change and occasionally fragment only to reintegrate at a later date. At 9000 pages a year it represents an enormous editorial task that has had to be undertaken by more professional offices. This transition has been helped through the development of electronic tools, but the editorial offices strive to retain their personal relationship with authors and reviewers. An enhanced international perspective recognises the widening contributions made by scientists beyond Europe and North America.