Why cumulative impacts assessments of hydrocarbon activities in the Arctic fail to meet their purpose

Regional Environmental Change - The Arctic Region is characterised by vulnerable ecosystems and residing indigenous people, dependent on nature for subsistence fishing and hunting. The Arctic also...     

Urban community gardening,social capital,and "integration" – a mixed method exploration of urban "integration-gardening" in Copenhagen,Denmark

ABSTRACT

This study examines a community garden in Copenhagen, Denmark, "The Urban Integration Gardens" that endeavours to strengthen social integration in the local multicultural neighbourhood. The "community" in the gardens is explored, with a focus on how they foster social capital, particularly opportunities for "bridging" social capital. A mixed-methods approach is used, by employing a qualitative analysis of gardeners’ perceptions of "community", diversity and inclusivity, through the lens of "cognitive" social capital, and the meanings the gardeners assign to their experiences, and how they understand their involvement in the gardens. We also examine "structural" dimensions of social capital, involving quantitative data from a questionnaire and data from Statistics Denmark, comparing data concerning socio-demographic backgrounds from gardeners and residents in the local neighbourhood and Copenhagen. Major findings include that the garden generates both bonding and bridging "cognitive" social capital, and the gardeners consistently agreed that the garden has a strong community, and is permeated by diversity and inclusivity. Nonetheless, data from Denmark’s Statistics Office reveal that the garden does not "represent" the diversity in the neighbourhood regarding the distribution of members with a Western/non-Western background, as well as social class. This suggests that endeavours to involve co-citizens with non-Western backgrounds and gardeners with lower social status are restrained by potential structural barriers, which limits the "width" of bridging social capital in the garden.     

Comprehensive prenatal diagnostics: Exome versus genome sequencing

Objective

This study aimed to assess the diagnostic yield of prenatal genetic testing using trio whole exome sequencing (WES) and trio whole genome sequencing (WGS) in pregnancies with fetal anomalies by comparing the results with conventional chromosomal microarray (CMA) analysis.

Methods

A total of 40 pregnancies with fetal anomalies or increased nuchal translucency (NT ≥ 5 mm) were included between the 12th and 21st week of gestation. Trio WES/WGS and CMA were performed in all cases.

Results

The trio WES/WGS analysis increased the diagnostic yield by 25% in cases with negative CMA results. Furthermore, all six chromosomal aberrations identified by CMA were independently detected by WES/WGS analysis. In total, 16 out of 40 cases obtained a genetic sequence variant, copy number variant, or aneuploidy explaining the phenotype, resulting in an overall WES/WGS diagnostic yield of 40%. WES analysis provided a more reliable identification of mosaic sequence variants than WGS because of its higher sequencing depth.

Conclusions

Prenatal WES/WGS proved to be powerful diagnostic tools for fetal anomalies, surpassing the diagnostic yield of CMA. They have the potential to serve as standalone methods for prenatal diagnosis. The study highlighted the limitations of WGS in accurately detecting mosaic variants, which is particularly relevant when analyzing chorionic villus samples.     

Making work environment auditable – A ‘critical case’ study of certified occupational health and safety management systems in Denmark

This paper discusses the impact of certification on occupational health and safety management (OHSM) systems. Most research in the field has focused on how well such systems comply with voluntary standards such as OHSAS 18001 or with national and international legislation. However, this paper shows that even in cases of compliance, the certified systems have problems dealing with a range of contemporary complex work environment issues. Furthermore, certification also transforms the kinds of topics addressed and the procedures and activities applied in the system. Using the (in many ways successful) development of certified OHSM system in a manufacturing company in Denmark as a critical case, we demonstrate how certified OHSM systems unintentionally yet actively create an environment of ‘measurable and auditable facts’ shaped not only in response to legal and market demands for a safe work environment, but also as a consequence of the external demands for a visible and accountable work environment standard. We show how certified OHSM systems function like a hinge between internal operations and an external audience in a globalized market, thus giving priority to work environment issues that may later become demonstrable guarantees for a safe and healthy work environment. Thus the certified management system does not necessarily tackle the most urgent work environment issues and may exclude important aspects of the work environment such as psychosocial factors.     

依据(代)生物体对化学品的反应预测对生态系统服务功能的影响

保护生态系统服务功能越来越多地被作为风险评估的目标，但是目前生态风险评估的终点和评估生态系统服务功能受到的潜在影响之间有很大的差距。作者提出了一个框架，将常用的生态毒理学终点与对种群和群落的影响以及生态系统的服务功能联系起来。这个框架建立在机制效应模型的长足进步上，这些模型旨在跨越多种生物组织，并解释各种生物相互作用和反馈。为了说明这一点，作者引入了2个研究案例，它们采用了已完善和已验证的机制效应模型：鱼种群的inSTREAM个体模型和AQUATOX生态系统模型。他们还展示了动态能量平衡理论可以为解释组织级毒性提供一种通用货币。他们认为，一个基于机制模型的框架，可以预测化学品暴露对生态系统服务的影响，再结合经济估值，可以为环境管理提供一种有用的方法。作者强调了使用这个框架的潜在好处以及未来工作中需要解决的挑战。
精选自Forbes, V. E., Salice, C. J., Birnir, B., Bruins, R. J.F., Calow, P., Ducrot, V., Galic, N., Garber, K., Harvey, B. C., Jager, H., Kanarek, A., Pastorok, R., Railsback, S. F., Rebarber, R. and Thorbek, P. (2017), A framework for predicting impacts on ecosystem services from (sub)organismal responses to chemicals. Environmental Toxicology and Chemistry, 36: 845–859. doi: 10.1002/etc.3720
详情请见http://onlinelibrary.wiley.com/doi/10.1002/etc.3720/full