Thyroid disruption at birth due to prenatal exposure to beta-hexachlorocyclohexane

OBJECTIVE: Thyroid hormones play an important role in human brain development, and some organochlorine compounds (OCs) act as thyroid disruptors. The objective of the present study was to evaluate the association between prenatal exposure to organochlorine compounds and thyroid function in newborns from a general population birth cohort in Menorca, with an a-priori specific focus on beta-HCH. METHODS: Levels of polychlorinated biphenyls (PCB congeners 28, 52, 101, 118, 138, 153 and 180), hexachlorobenzene (HCB), beta-hexachlorocyclohexane (beta-HCH), dichlorodiphenyl dichloroethylene (p'p'-DDE) and dichlorodiphenyl trichloroethane (p'p-DDT) in cord serum, and thyrotropin (TSH) concentration in plasma three days after birth were measured in 387 newborns from Menorca. The TSH concentration was categorized (high or low), except for 27 children whose TSH levels were quantified. RESULTS: Levels of beta-HCH and PCB-153 were positively related to TSH concentrations (gestational age-adjusted coefficient (p-value): 0.26 (p = 0.006) and 0.31 (p = 0.050), respectively). CONCLUSIONS: beta-HCH is potentially a new thyroid disrupting compound, deserving special interest in future studies given its high body burden in humans.     

Microsatellite data reveal fine genetic structure in male Guiana dolphins (<Emphasis Type="Italic">Sotalia guianesis)</Emphasis> in two geographically close embayments at south-eastern coast of Brazil

A large macrogeographic differentiation has been observed among Sotalia guianensis populations along the South American coast. However, no genetic structure has been detected so far in closely distributed populations of this species, even though it has been observed in other cetaceans. Here, we examined the fine scale population structure for the largest populations of S. guianensis inhabiting Sepetiba and Paraty embayments at the south-eastern coast of Rio de Janeiro, Brazil. Analysis of mitochondrial DNA (mtDNA) control region sequences failed to detect variability among sequences. Conversely, evidence of significant male population structure was found on the basis of ten nuclear microsatellite loci. Surprisingly, the microsatellite markers were able to distinguish between individuals from the two embayments located 60 km apart. The results suggest that differences in habitat type and behavioral specializations are likely to explain the patterns of genetic structure. These findings should provide baselines for the management of communities exposed to increasing human-driven habitat loss.     

Lock-release gravity currents propagating over roughness elements

Environmental Fluid Mechanics - The influence of bottom roughness on the development of lock-release gravity currents is investigated through laboratory experiments using Particle Image...     

Bioassay-guided isolation of allelochemicals from Avena sativa L.: allelopathic potential of flavone C-glycosides

The allelopathic potential of oat (Avena sativa L., var. Argentina, Poaceae, Cyperales) was investigated under field and laboratory conditions. In field trials, oat plants provided an effective control of weeds, showing a species-specific impact: the most abundant weed species, Picris echioides was reduced by 94% in number of individuals. Aerial parts of oat plants, harvested immediately before soil incorporation, were utilized in a bioassay-guided isolation, which was aimed at identifying the phytotoxic compounds in a methanol/water extract of the aerial parts of the plants. Further partitions of extract gave an active n-butanol portion composed of flavonoids and saponins. Phytotoxic activity was detected for the flavonoid fraction, whereas no activity was found for the saponin mixture. Germination of an indicator species, lettuce (Lactuca sativa L.), was completely inhibited at flavonoid concentrations of 6.7, 10.0, and 20.0 mg/mL, and conversely the number of abnormal seedlings was greatly increased from 2% of control to over 96% at concentrations equal to 6.7 and 10.0 mg/mL. Analysis of the flavonoid fraction by ESI-MS techniques identified two components of the mixture as isoorientin 2-O-glucoside and isovitexin 2″-O-arabinoside. Saponins were characterized as avenacoside A, avenacoside B, 26-desglucoavenacoside A, and 26-desglucoavenacoside B. Both flavone C-glycosides and saponins were isolated previously from oat.     

Environmental pollution of China to foreign investors: detrimental or beneficial?

Environmental Science and Pollution Research - This study investigates the dynamic linkage among foreign direct investment, energy consumption, and environmental pollution of China spanning from...     

Congener distribution of polybrominated diphenyl ethers in feral carp (Cyprinus carpio) from the Llobregat River, Spain

Feral carp were collected at two Spanish rivers, Anoia and Cardener, showing PBDE levels from 29 to 638 ng/g lipid weight (lw) and from 54 to 744 ng/g lw, respectively. Sediments were also collected, showing PBDE contamination between 2 and 10 ng/g dry weight (dw). Differences in PBDE profiles between sediments and fish were noticed. Contribution of BDE-47 in sediment was up to 11%, whereas it contributed 37-90% of PBDEs in fish. Similar results were observed for BDE-154, which was only detected in one sediment sample, but presented high contribution in carp. In contrast, BDE-99 contributed up to 32% in sediments, but it was not detected in fish. Similar results were observed for BDE-153, BDE-183 and BDE-209. The main reason for their concentration decrease or absence in biota may be due to low bioavailability potential or due to biotransformation processes.     

Bioaccumulation of paraquat by Lumbriculus variegatus in the presence of dissolved natural organic matter and impact on energy costs, biotransformation and antioxidative enzymes

Dissolved organic matter from natural sources (DNOM) is omnipresent in aquatic ecosystems. Besides affecting bioavailability of substances including xenobiotics, it directly influences physico-chemistry of the habitat and there is increasing evidence for it is interaction with organisms. We investigated direct and interacting effects of DNOM from three sources, Lake Valkea-Kotinen, Svartberget Brook, and Lake Fuchskuhle with the herbicide paraquat on the oligochaete worm Lumbriculus variegatus. Bioavailability of paraquat to L. variegates as well as activities of antioxidative enzymes catalase (CAT) and peroxidase (POD) and biotransformation enzyme soluble glutathione S-transferase (sGST) were assessed without and in the presence of DNOM. Furthermore, metabolic heat dissipation due to the exposure was quantified. Uptake of paraquat into the worms was concentration dependently reduced by DNOM, and with differences concerning the DNOM sources. sGST and CAT responded with increased activities to DNOM (5 and 25 mg C l-1) and paraquat (5.0, 50, and 500 microg l-1) separately. Paraquat at 5.0 microg l-1 and DNOM in combination caused increased activities of sGST, especially at 5 mgC l-1, but inhibition of CAT activities. The latter probably occurred due to saturation of the enzyme. Changes in enzyme activities were independent from the source of DNOM. Increasing DNOM concentrations raised metabolic heat dissipation in L. variegatus with maximum at 3h of exposure. In the combined treatments, metabolic heat dissipation changed more due to the source of DNOM than due to the bioavailability of paraquat.     

Survey of organotin compounds in rivers and coastal environments in Portugal 1999-2000

In the period from April 1999 to May 2000, organotin pollution, namely butyl and phenyltins, was investigated in coastal and continental waters (46 stations), estuarine sediments (15 stations) and mussels (Mytilus galloprovincialis) (13 stations) throughout Portugal. Sampling points were chosen in areas of specific industrial, agricultural and harbor activities. Butyltins (BTs) were the only tin species identified of which tributyltin (TBT) was found in the whole area. Concentrations of TBT in river water ranged from 3 to 30 ng L(-1) (as Sn), marine sediment ranged from 4 to 12 microg kg(-1) (as Sn), whereas concentrations in mussel tissue ranged from 2.5 to 490 microg kg(-1) (as Sn). Given that some water samples appeared to be contaminated by higher monobutyltin (MBT) and dibutyltin (DBT) concentrations, the role of biological degradation and direct inputs from agricultural and industrial applications areas are discussed. The study compares depleted butyltin pollution in sediments and mussels of the Portuguese coastline associated with antifouling paints with previously reported levels. Inputs in river waters are more related to (i) PVC leaching and (ii) industrial sources, in some cases discharged by municipal wastewaters.     

A new environmental chamber for evaluation of gas-phase chemical mechanisms and secondary aerosol formation

A new state-of-the-art indoor environmental chamber facility for the study of atmospheric processes leading to the formation of ozone and secondary organic aerosol (SOA) has been constructed and characterized. The chamber is designed for atmospheric chemical mechanism evaluation at low reactant concentrations under well-controlled environmental conditions. It consists of two collapsible 90 m³ FEP Teflon film reactors on pressure-controlled moveable frameworks inside a temperature-controlled enclosure flushed with purified air. Solar radiation is simulated with either a 200 kW Argon arc lamp or multiple blacklamps. Results of initial characterization experiments, all carried out at 300–305 K under dry conditions, concerning NO_x and formaldehyde offgasing, radical sources, particle loss rates, and background PM formation are described. Results of initial single organic–NO_x and simplified ambient surrogate–NO_x experiments to demonstrate the utility of the facility for mechanism evaluation under low NO_x conditions are summarized and compared with the predictions of the SAPRC-99 chemical mechanism. Overall, the results of the initial characterization and evaluation indicate that this new environmental chamber can provide high quality mechanism evaluation data for experiments with NO_x levels as low as 2 ppb, though the results indicate some problems with the gas-phase mechanism that need further study. Initial evaluation experiments for SOA formation, also carried out under dry conditions, indicate that the chamber can provide high quality secondary aerosol formation data at relatively low hydrocarbon concentrations.