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41.
About a quarter of the human diseases occurs for exposure to air pollution. The male reproductive system, and especially spermatogenesis, seems to be particularly sensitive. As result, male infertility is increasing in industrial countries becoming a top priority for public health. In addition to psychological distress and economic constraints, poorer semen quality may have trans-generational effects including congenital malformations in the offspring and predispose to later onset adult diseases. Genetic and epigenetic alterations are involved in the failure of spermatogenesis. In this paper, we reviewed the major evidences of the effects of air pollutants on male infertility as well as the role of sperm DNA damage and epigenetic changes in affecting spermatogenesis. A better knowledge on the effects of air contaminants on the molecular mechanisms leading to infertility is of huge importance to help clinicians in identifying the cause of infertility but above all, in defining preventive and therapeutic protocols.  相似文献   
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Purpose  

Polychlorinated biphenyls (PCBs), dichlorodiphenyltrichloroethane (DDT) and PCB congeners accumulation profile were measured in the liver of two torpedinid species (Torpedo nobiliana and Torpedo marmorata) from the Mediterranean Sea (Adriatic Sea) in order to investigate the relative toxicological impact of these highly toxic PCBs in the organisms in question.  相似文献   
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Temporal dynamical analysis in fire sequences recorded from 1992 to 2005 in a fire-vulnerable area of Patagonia (Argentina) was performed by using the Allan Factor statistics. Three typologies of fires were investigated: forest, steppe and urban. The obtained results show the presence of annual periodicities, superimposed to a time-scaling behaviour, which characterize the point processes of fires as fractal time processes with a rather high degree of time-clusterization of the events.  相似文献   
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