Pharmacokinetic model of dioxin and furan levels in adipose tissue from Sawmill work involving chlorophenate fungicides

Sawmill workers in British Columbia (B.C.), Canada, have been exposed to chlorophenate fungicides which are known to be contaminated with polychlorinated dibenzo-p-dioxins (PCDDs) and polychlorinated dibenzofurans (PCDFs). Due to concern about the potential of these workers to have significant body burdens of PCDD/Fs, and the absence of measurements in these worker, a single-compartment pharmacokinetic model was developed to estimate the concentration of PCDD/Fs in the fat tissue of the sawmill workers. Data from a large cohort of B.C. sawmill workers and literature-based data on chlorophenate exposures and PCDD/F concentrations in chlorophenates were used in Monte Carlo simulations to predict a PCDD/F body burden distribution. The median concentrations of HxCDF and HpCDF predicted using the model for the B.C. sawmill worker population exceeded the range measured in unexposed populations. PeCDF and OCDF concentrations exceeded the range measured in unexposed populations at the 70th percentile of the model-predicted distribution, and PeCDD at the 90th percentile. The primary limitation of the model was the scarcity of input data about actual dermal and inhalation exposures to chlorophenates.     

The 1928 Eruption of Mount Etna Volcano, Sicily, and the Destruction of the Town of Mascali

In November 1928 there was an eruption of Mount Etna, Sicily, which led to lava largely destroying the town of Mascali, situated low on the eastern flank of the volcano. Destruction of the town took just over a day but there was an orderly evacuation of its inhabitants and, with help from the military, families were able to remove furniture and fittings from their houses. Evacuees were relocated to nearby towns staying with relatives, friends or in hired apartments. Rebuilding Mascali provided an opportunity for the fascist government of the time to demonstrate efficient centralised planning. A completely new town was built on a grid-iron plan with many of the buildings reflecting the 'fascist architecture' of the time. The town was complete by 1937 and housing condztzons were very advanced in comparison with other towns in the region. The 1928 eruption is important as it was the most destructive on Etna since 1669 when the city of Catania was overwhelmed. In terms of hazard and risk assessment the 1928 eruption demonstrates that lava can reach the lower flanks of the volcano within a short period after the onset of an eruption.     

Health implications of the Tumaco earthquake, Colombia, 1979

A retrospective study of the effects of the Tumaco earthquake of 1979 shows a smaller number of deaths and injuries than in earthquakes of similar magnitude that have occurred elsewhere, which is probably related to the type of building. Most of the deaths were caused by a tsunami. Proportionally the mortality was higher in the 0 to 4 age group. Among the injured, most of the lesions were minor. Morbidity was higher in the over 45 years age group, and lower among the "under-fives." There was an evident need for a simple "disaster medical record card." Coordination among the different relief agencies could have been better.     

Accounting for the quality of work life

This study describes the development and issuance of an independent report on the quality of work life in a Corporation. The theory underlying the report, criteria, definitions, measurement procedures, the properties of the measures, and report itself are presented. A survey indicating a favourable reception to the data by stockholders, financial analysts, and employees is analysed. Recommendations for increased collaboration between accountants and behavioural scientists in the measurement and assessment of the quality of work life are presented in an effort to stimulate further research in the development of standardized measures and in the preparation of independent reports on the quality of work life in organizations.     

Behavior of dialifor, dimethoate, and methidathion in artificially fortified grape juice processed into wine.

Dialifor and methidathion were added to diluted "Zinfandel" grape concentrate at 25 ppm and dimethoate at 1.0 and 25 ppm prior to fermentation with Saccharomyces cerevisiae. The finished wine 56 days later contained 10% (2.5 ppm) of the dialifor, 46% (12 ppm) of the methidathion and 85% (21 and 0.98 ppm) of the dimethoate added to the grape must. Residues in wine stored at 24 degrees C dissipated by hydrolysis; half-lives in wine were 7 days for dialifor and methidathion and 30 days for dimethoate. Residues were unchanged in wine in frozen storage for one year. Analysis of seven commercial wines for dimethoate indicated less than 0.03 ppm dimethoate was present; identity could not be confirmed by thin-layer chromatography at this level.     

Environmental controls of patch-reef growth and development

The effects of predominant currents on the morphology of coral reefs has been studied in the leeward patch reefs of Anegada, British Virgin Islands. Measurements of current velocity and direction and sediment characteristics together with mapping of approximately 31 patch reefs within a 2 km² area suggest that even under relatively low but constant current velocities (surface current 20 cm sec^-1) the major reef-building corals show definite distribution patterns on the reef. The currents also appear to be responsible, in part, for marked orientation and elongation of patch reefs in a north-west/ south-east direction and for a gradation of patch-reef type across the study area.