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91.
Introduction of combined screening with maternal serum alpha-fetoprotein and human chorionic gonadotropin (MShCG) assays for fetal chromosome defects requires establishment of the normal range for twins. This report documents that the normal range for MShCG between 15 and 19 weeks in twin gestations was 1.84–2.41 multiples of the singleton median. Of the 192 twin pregnancies studied, 31.7 and 47.9 per cent had MShCG values ≥2.5 and ≥ 2.0 multiples of the singleton median, respectively. 相似文献
92.
Linda Nebiolo Mehmet Ozturk Bruno Brambati Susan Miller Jack Wands Aubrey Milunsky MD 《黑龙江环境通报》1990,10(9):575-581
The aim of this study was to determine the efficacy of combined maternal serum alpha-fetoprotein (MSAFP) and maternal serum human chorionic gonadotropin (MShCG) screening in detecting chromosome defects in the first trimester of pregnancy. Sera of 492 women (previously assayed for MSAFP) were analysed for MShCG under code without knowledge of cytogenetic results. Overall, 48 of 492 patients (9·8 per cent) had either an MSAFP multiple of the median ⩽0·5 or an MShCG β/a z ratio multiple of the median ⩽ 0·25, eight of whom had a fetus with a serious chromosome defect. A third of fetuses with Down' s syndrome and 83 per cent with trisomy 18 were detected at a potential‘cost’ of providing chorionic villus sampling or amniocentesis in 8·6 percent of women screened. 相似文献
93.
Michael R. Heithaus Aaron J. Wirsing Lawrence M. Dill Linda I. Heithaus 《Marine Biology》2007,151(4):1455-1461
Tiger sharks are important predators in the seagrass ecosystem of Shark Bay, Australia. Although sharks appear to return to
a long-term study site within the Eastern Gulf periodically, the extent of their long-term movements is not known. Five sharks
fitted with satellite transmitters showed variable movement patterns. Three sharks remained within the Shark Bay region and
another made a 500 km round-trip excursion to oceanic waters northwest of the bay. These four sharks showed relatively low
displacement rates relative to sharks tracked over shorter time periods, suggesting that sharks move through large home ranges
that include Shark Bay. Although no reliable position fixes were obtained for the fifth shark, we were able to use the timing
of satellite uplinks and the position of the satellite to determine that it had moved at least 8,000 km to the coastal waters
of southeast Africa in 99 days—the longest recorded movement by a tiger shark. This movement and previously documented trans-Atlantic
movements suggest that tiger shark populations may mix across ocean basins and that tiger sharks are subject to anthropogenic
effects at great distances from protected waters. Finally, our method for using single satellite uplinks may be useful in
estimating movements for wide-ranging species that rarely provide high quality location estimates. 相似文献
94.
R. Burnett S. Bartlett D. Krewski G. Robert M. Raad-Young 《Environmental and Ecological Statistics》1994,1(4):325-332
A statistical model for longitudinal count data is used to examine the potential adverse health effects of ambient air pollution. Daily respiratory admissions to 164 acute care hospitals in Ontario are obtained for the period 1983 to 1988. Estimates of ozone levels in the vicinity of each hospital are determined from air pollution monitoring stations maintained by the Ontario Ministry of the Environment. Generalized estimating equation methods are used to make inferences about the regression and overdispersion parameters. The admission data display little evidence of serial correlation and extra Poisson variation. However, admission rates vary considerably among hospitals. This latter source of variation needs to be taken into account in examining the effects of air pollution on respiratory health status. 相似文献
95.
Subordinate males are more likely to help if unrelated to the breeding female in cooperatively breeding white-browed scrubwrens 总被引:2,自引:0,他引:2
Subordinates in communally breeding groups of birds usually help to provision nestlings, but in some species helping-at-the-nest
is facultative. In species in which groups usually contain relatives, subordinates either always feed young or are more likely
to do so when breeding dominants are close relatives, suggesting that benefits of helping collateral kin are important. In
other species, adult group members are unrelated to each other and males may only feed young if they have gained paternity,
showing that cooperation is related to the mating system. The white-browed scrubwren, Sericornis frontalis, is a communally breeding species in which most groups consist of a simple pair or a dominant pair with a subordinate male.
Subordinate males either fed nestlings in a given nest at a rate comparable to the dominants, or did not feed them at all.
Breeding groups usually formed through natal philopatry of males, so that about 80% of subordinates were closely related to
one or both members of the dominant pair. However, because of death and dispersal, 54% of subordinates were unrelated to the
resident female. Although subordinates with their mother fed nestlings in 48% of cases, they fed offspring in 75% of cases
if their mother had been replaced by an unrelated female, suggesting that their decision to help is influenced by the opportunity
to mate with the female. Supporting this conclusion, relatedness to the dominant male did not affect subordinate behaviour,
and genetic studies showed that subordinates often gained paternity if unrelated to the female. Thus, paradoxically, provisioning
nestlings is related to the opportunity for mating in a society in which there is natal philopatry and subordinates are usually
related to one or both members of the dominant pair.
Received: 25 January 1997 / Accepted after revision: 1 May 1997 相似文献
96.
P Ed Parnell Paul K Dayton Cleridy E Lennert-Cody Linda L Rasmussen James J Leichter 《Ecological applications》2006,16(3):945-962
The design of marine reserves is complex and fraught with uncertainty. However, protection of critical habitat is of paramount importance for reserve design. We present a case study as an example of a reserve design based on fine-scale habitats, the affinities of exploited species to these habitats, adult mobility, and the physical forcing affecting the dynamics of the habitats. These factors and their interaction are integrated in an algorithm that determines the optimal size and location of a marine reserve for a set of 20 exploited species within five different habitats inside a large kelp forest in southern California. The result is a reserve that encompasses approximately 42% of the kelp forest. Our approach differs fundamentally from many other marine reserve siting methods in which goals of area, diversity, or biomass are targeted a priori. Rather, our method was developed to determine how large a reserve must be within a specific area to protect a self-sustaining assemblage of exploited species. The algorithm is applicable across different ecosystems, spatial scales, and for any number of species. The result is a reserve in which habitat value is optimized for a predetermined set of exploited species against the area left open to exploitation. The importance of fine-scale habitat definitions for the exploited species off La Jolla is exemplified by the spatial pattern of habitats and the stability of these habitats within the kelp forest, both of which appear to be determined by ocean microclimate. 相似文献
97.
Kate K. Mulvaney Patrick Woodson Linda Stalker Prokopy 《Environmental management》2013,51(5):1012-1024
Benton County, in north-central Indiana, USA has successfully sited more than 500 turbines. To understand Benton County’s acceptance of wind farms, a holistic case study was conducted that included a document review, a survey of local residents and interviews with key stakeholders. Survey questionnaires were sent to 750 residents asking questions about attitudes toward the wind farms, perceived benefits and impacts from the wind farms, environmental attitudes, and demographic information. Key stakeholders were also interviewed for a deeper understanding of the historical timeline and community acceptance of the wind farm development. While there is limited opposition to the turbines, on the whole the community presents a front of acceptance. Financial, rather than environmental, benefits are the main reason for the acceptance. Although significant in other case studies, transparency and participation do not play a large role in Benton County’s acceptance. Most residents are not concerned with either visual impacts or noise from the wind turbines. More concrete benefits to the community, such as reduced energy bills for county residents, could help to extend acceptance even further within the community. Although there are concerns about the acceptance of wind farms and the impacts of those farms on local residents in both peer-reviewed literature and popular media, we found little evidence of those concerns in Benton County. Instead, we found Benton County to be a community largely accepting of wind farms. 相似文献
98.
Supriyo De Somiranjan Ghosh Raghunath Chatterjee Y-Q Chen Linda Moses Akanchha Kesari Eric P. Hoffman Sisir K. Dutta 《Environment international》2010,36(8):907-917
In this study we have examined the effect of exposure to different congeners of PCBs and their role in oxidative stress response. A metabolically competent human liver cell line (HepG2) was exposed with two prototype congeners of PCBs: coplanar PCB-77 and non-coplanar PCB-153. After the predetermined times of exposure (0–24 h) at 70 μM concentration, the HepG2 cells showed significant apoptotic changes by fluorescent microscopy after 12 h of exposure. Gene set enrichment analysis (GSEA) identified oxidative stress as the predominant enrichment. Further, paraquat assay showed that PCB congeners lead to oxidative stress to different extents, PCB-77 being more toxic. This study, with emphasis on all recommended microarray quality control steps, showed that apoptosis was one of the most significant cellular processes as a result of oxidative stress, but each of these congeners had a unique signature gene expression, which was further validated by Taqman real time PCR and immunoblotting. The pathways involved leading to the common apoptotic effect were completely different. Further in-silico analysis showed that PCB-153 most likely acted through the TNF receptor, leading to oxidative stress involving metallothionein gene families, and causing apoptosis mainly by the Fas receptor signaling pathway. In contrast, PCB-77 acted through the aryl hydrocarbon receptor. It induced oxidative stress through the involvement of cytochrome P450 (CYP1A1) leading to apoptosis through AHR/ARNT pathway. 相似文献
99.
Linda S. Gaulke Xiao Weiyang Andrew Scanlon Amanda Henck Tom Hinckley 《Environmental management》2010,45(1):93-104
The administration of Jiuzhaigou National Park in Sichuan Province, China, is in the process of considering a range of upgrades
to their sanitation and wastewater treatment systems. Their case history involves an ongoing series of engineering design
flaws and management failures. The administration of the Park identified sustainability, environmental protection, and education
goals for their sanitation and wastewater treatment system. To meet the goal of sustainability, environmental and economic
concerns of the Park’s administration had to be balanced with socio-cultural needs. An advanced reconnaissance method was
developed that identified reasons for previous failures, conducted stakeholder analysis and interviews, determined evaluation
criteria, and introduced innovative alternatives with records of successful global implementations. This evaluation also helped
the Park to better define their goals. To prevent future failures, the administration of the Park must commit to a balanced and thorough evaluation process for
selection of a final alternative and institute effective long-term management and monitoring of systems. In addition, to meet
goals and achieve energy efficient, cost-effective use of resources, the Park must shift their thinking from one of waste
disposal to resource recovery. The method and criteria developed for this case study provides a framework to aid in the successful
implementation of sanitation projects in both underdeveloped and developed areas of the world, incorporating socio-cultural
values and resource recovery for a complex group of stakeholders. 相似文献
100.
Educators recognize the ecological, economic, and social components of environmental sustainability. For community-based programs, there is another sustainability trio that, if neglected, will lead to a decline in program quality and function. To be sustainable over the long term, community-based programs must have superior educational quality, clear organizational structure, and continued financial stability. Many educational outreach programs that have neglected this sustainability trio have been weakened or eliminated as they are not seen as priority items during budget reductions. The Master Gardener Program exemplifies this premise, representing a cadre of tens of thousands of university-trained volunteer educators who deliver environmental education to their communities. Over the years, the vision for educational quality, use of clear organizational structures fitting an increased reliance on volunteers, and securing of outside funding for sustainability education have waned in many states, resulting in a lack of university leadership and programmatic devolution. We propose revising outreach education to align with the best practices in adult pedagogy and science by developing a centralized organizational structure and by looking outside traditional university resources for funding opportunities. These strategies can easily be adapted for other community-based outreach programs. 相似文献