排序方式: 共有48条查询结果,搜索用时 15 毫秒
41.
McKelvie JR Wolfe DM Celejewski MA Alaee M Simpson AJ Simpson MJ 《Environmental pollution (Barking, Essex : 1987)》2011,159(12):3620-3626
Nuclear magnetic resonance (NMR) - based metabolomics has the potential to identify toxic responses of contaminants within a mixture in contaminated soil. This study evaluated the metabolic response of Eisenia fetida after exposure to an array of organic compounds to determine whether contaminant-specific responses could be identified. The compounds investigated in contact tests included: two pesticides (carbaryl and chlorpyrifos), three pharmaceuticals (carbamazephine, estrone and caffeine), two persistent organohalogens (Aroclor 1254 and PBDE 209) and two industrial compounds (nonylphenol and dimethyl phthalate). Control and contaminant-exposed metabolic profiles were distinguished using principal component analysis and potential contaminant-specific biomarkers of exposure were found for several contaminants. These results suggest that NMR-based metabolomics offers considerable promise for differentiating between the different toxic modes of action (MOA) associated with sub-lethal toxicity to earthworms. 相似文献
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P. Pessala J. Kernen E. Schultz T. Nakari M. Karhu H. Ahkola J. Knuutinen S. Herve J. Paasivirta J. Ahtiainen 《Chemosphere》2009,75(11):1506-1511
The aerobic biodegradation of commercial nonylphenol ethoxylate (NPE) mixture and alkali lignin was studied using the OECD headspace test accompanied by the simultaneous measurement of ecotoxicity directly from the biodegradation liquors and by the follow-up of the chemical composition of the studied chemicals. NPE degradation was dependent on the inoculum source: approximately 40% of NPE was mineralized into CO2 during the 4-week experiment when inoculum from Helsinki City wastewater treatment plant (WWTP) was used, and only 12% was mineralized when inoculum from Jyväskylä City WWTP was used. Chemical analyses revealed a shift in the ethoxylate chain length from longer to shorter soon after the beginning of the NPE biodegradation tests. At the same time also toxicity (reverse electron transport assay, RET) and estrogenic activity (human estrogen receptor yeast) measured directly from the biodegradation liquors decreased. In case of alkali lignin, approximately 11% was mineralized in the test and chemical analysis showed in maximum a 30% decrease in lignin concentration. Toxicity of lignin biodegradation liquors started to decrease in the beginning of the test, but became more toxic towards the end of the test again. Especially RET assay proved to be sensitive enough for measuring toxicity changes directly from biodegradation liquors, although a concentrating treatment of the liquors is recommended for a more detailed characterization and identification of toxic metabolites. 相似文献
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Kauser Jahan Raúl Ordóñez Ravi Ramachandran Shira Balzer Michael Stern 《Water, Air, & Soil Pollution: Focus》2008,8(3-4):395-404
Nonylphenol is the primary breakdown product of nonylphenol ethoxylates, a certain class of nonionic surfactants. Nonylphenol
has been found to be toxic to aquatic organisms and has been suspected of being harmful to humans due to its xenoestrogenic
properties. Although there are known releases of nonylphenol to the environment, there is a lack of data describing the extent
of biodegradation. This study thus focuses on much needed information on the biodegradation kinetics of nonylphenol. Oxygen
uptake, cell growth and nonylphenol removal data were collected using batch reactors in an electrolytic respirometer. Nonylphenol
removal, cell growth and substrate removal rates were modeled by the Monod, Haldane, Aiba, Webb, and Yano equations. The differential
equations were solved by numerical integration to simulate cell growth, substrate removal, and oxygen uptake as a function
of time. All models provided similar results with the Haldane model providing the best fit. The values of the kinetic parameters
and the activation energy for nonylphenol were determined. These values can be used for predicting fate and transport of nonylphenol
in the environment. The validity of applying each model to the biodegradation of nonylphenol was analyzed by computing the
R
2 values of each equation. 相似文献
44.
To explore the effects of nonylphenol on brain development-associated gene expression profiles of F1 generation rats by means of microarray technique. The mRNA were extracted respectively from the brain of 2-day-old F1 generation rats whose F0 male generation were tested with and without nonylphenol, respectively, then reversely transcribed to cDNA and labeled with cy5 and cy3 fluorescence. Subsequently,the cDNA probes were hybridized to the Mouse40S cDNA microarray and the fluorescent signals of cy5 and cy3 were scanned and analyzed. Sixteen identified genes expressed differently, including 13 down-regulated in which five were related to brain function and development. Nonylphenol can effect the brain function in many ways, mainly disturb metabolism, development and differentiation of neurocyte, and synthesis and release of neurotransmitter. 相似文献
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壬基酚是环境内分泌干扰物质中具有代表性的物质,非离子表面活性剂壬基酚聚氧乙烯醚在环境中的降解产物,对生物体造成很大危害。目前检测水样中壬基酚的主要方法是采用GC—MS和HPLC,预处理主要采用固相萃取和液一液萃取。研究表明自来水厂的常规处理工艺对于水中壬基酚的去除有限;近年来倍受关注的深度处理工艺如活性炭吸附等物理方法... 相似文献
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Kailin Xu Li Jiao Chuqiao Wang Yiming Bu Yuling Tang Liwei Qiu Qiuya Zhang Liping Wang 《环境科学学报(英文版)》2022,34(1):93-103
Nonylphenol(NP) residues, as a typical endocrine disrupting chemical(EDC), frequently exist in sewage, surface water, groundwater and even drinking water, which poses a serious threat to human health due to its bioaccumulation. In order to remove NP, a series of MIL-100(Fe)/Zn Fe2O4/flake-like porous carbon nitride(MIL/ZC) was synthesized through in-situ synthesis at room temperature. High performance of ternary MIL/ZC is used to degrade NP under visible light irradiation. ... 相似文献
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