乡村人居环境:人居环境科学研究的新领域

乡村人居环境是人居环境科学的重要构成部分,随着城市化的快速推进,乡村人居环境日益恶化.人居环境科学研究存在明显缺陷,即人居环境研究的"城市主义"倾向明显,忽视了乡村人居环境研究.分析了开展乡村人居环境研究的重要性和紧迫性,评述了国内外的相关研究成果,提出了乡村人居环境研究的多维视角,即基于农户空间行为的乡村人居环境研究、乡村人居环境的地域文化与发展模式研究、乡村人居环境与空间规划研究、基于"3S"技术的乡村人居环境研究、乡村人居环境的系统理论与发展战略研究.     

Evaluation of protective effects of sulforaphane on DNA damage caused by exposure to low levels of pesticide mixture using comet assay

The objective of the study was to evaluate the potential risk of DNA damage due to exposure to a mixture of the most widely used pesticides, namely endosulfan, chlorpyriphos and thiram at an environmentally relevant concentration (5 μM each) and the DNA protective capacity of sulforaphane (SFN) (10–30 μg/mL). DNA damage in human lymphocytes was ascertained with Single Cell Gel Electrophoresis (SCGE), also called Comet Assay. For positive control, H₂O₂ at 100 mM was used. The pesticide mixture produced DNA damage at the concentration used in the lymphocytes. SFN was able to offer a statistically significant (P < 0.01), concentration-dependant protection to DNA damage between 10–20 μg/mL in both the pre-incubation and co-incubation strategies. The results indicate that exposure to low levels of these pesticide mixtures can induce DNA damage, and the presence of SFN in diet may reduce the incidence of genetic damage, especially in farm workers. However, it is not clear whether SFN is involved in quenching of the free radicals generated by the pesticide mixture or it is involved in DNA repair mechanism.     

Obligations to animals are not necessarily based on rights

I offer a very qualified argument to the effect that rights are grounded in a certain sort of prejudice that privileges individualistic and perhaps masculinist ways of thinking about moral life. I also propose that we look carefully at other conceptions of social ontology and moral life, including the much discussed care conception.     

四川省科技人力资源潜力与结构变化

通过对四川省科技人力资源的潜力、结构变化的分析,提出建立统一规范的科技人才培养经费投入政策,加强科技人才资源的再开发,不拘一格引进科技人才,建立四川省科技人力资源监测系统等对策。     

生态环境与洪旱灾害

作者将自然运动与人类活动、生态环境与气候结合起来研究，求索洪旱灾害之谜，着重探讨了其中多种生态环境因素。由大灾后的反思，找出灾害加剧的人为原因是：人中激增、生态危机、水利失修等，提出必须加强防灾减灾的对策研究。     

Evaluation of Material Biodegradability in Real Conditions–Development of a Burial Test and an Analysis Methodology Based on Numerical Vision

This work validated a burial protocol for in situ testing and presents a robust, repeatable and time-saving technique to measure degraded areas in the sample, i.e. an image analysis method. 1440 specimens of degraded samples have been compiled in a data base. To this end, twenty samples presenting different levels of biodegradability (i.e. PHBV/HV, PLA, PCL, PCL-Starch, paper, PE, PE-Starch) were buried at 4 different locations and then disinterred at 4, 6, 9, 12, 18, and 24-month intervals. The biodegradation levels of these samples were determined by computing weight and area loss. Weight loss was measured after careful cleaning, whereas area loss was quantified using image analysis. Image analysis gives reliable information on visual pollution while only requiring a rudimentary and thus quicker cleaning of the samples.     

泥石流与人类经济活动

山地是泥石流与人类共存的环境,泥石流作用于山地环境,强烈地影响人类经济活动：人类经济活动也作用于山地环境,强烈地影响泥石流。泥石流对山地环境的危害,主要为破坏地表、破坏生态系统和淤堵江河;泥石流对人类及其经济活动的危害,主要为破坏城镇,村庄,工矿,交通水利水电工程,农田和人类自身的安全。泥石流危害的结果,能导致山地坡面破碎化、沟口沙石化、河床宽浅化和植被逆向演替化,以及耕地贫瘠化、经济发展滞后化和     

对灾害研究中几个问题的思考

对灾害研究中有关的几个问题进行了探讨。认为： 灾害学是最重要的自然社会科学; 人文灾害比自然灾害更具毁灭性; 研究人文灾害中的公路交通事故、核战争问题、人口问题、环境污染问题等具有重要的现实意义和深远的历史意义。     

Cultured human-cell-based bioassay for environmental risk management

Among bioassays for evaluating various impacts of chemicalson humans and ecosystems, those based on culturedmammalian-cells can best predict acute lethal toxicity to humans. Weexpect them to be employed in the future in environmentalrisk management alongside mutagenicity tests and endocrine-disrupting activity tests. We recently developed adisposable bioassay device that immobilizes humanhepatocarcinoma cells in a small micropipette tip. Thisenables very quick (within 2 h) evaluation of acute lethaltoxicity to humans. For bioassay-based environmentalmanagement, 2 promising approaches have been demonstrated bythe US-EPA: toxicity identification evaluation (TIE) andtoxicity reduction evaluation (TRE). The Japanese Ministryof Environment has been supporting a multi-center validationproject, aimed at assembling a bioassay database. To makefull use of these resources, we present a numerical modelthat describes contribution of individual chemical toobserved toxicity. This will allow the selection of the mosteffective countermeasure to reduce the toxicity. Bioassay-based environmental risk management works retrospectively,whereas impact assessment using substance flow models andtoxicity databases works prospective. We expect that these 2approaches will exchange information, act complementarily,and work effectively in keeping our environment healthy inthe 21st century.     

Determination of Q1, an unknown organochlorine contaminant, in human milk, Antarctic air, and further environmental samples

Q1, an organochlorine component with the molecular formula C(9)H(3)Cl(7)N(2) and of unknown origin was recently identified in seal blubber samples from the Namibian coast (southwest of Africa) and the Antarctic. In these samples, Q1 was more abundant than PCBs and on the level of DDT residues. Furthermore, Q1 was more abundant in seals from the Antarctic than the Arctic. To prove this assumption, gas chromatography-electron-capture negative ion mass spectrometry (GC/ECNI-MS), which is sensitive and selective for Q1, allowed for screening of traces of Q1 even in samples with particularly high levels of other organochlorine contaminants. Q1 was isolated by high-performance liquid chromatography (HPLC) from a skua liver sample. A 1:1 mixture with trans-nonachlor in electron-capture detectors (ECDs) was used to determine the relative response factor with ECNI-MS. The ECNI-MS response of Q1 turned out to be 4.5 times higher than that of trans-nonachlor in an ECD. With GC/ECNI-MS in the selected ion-monitoring mode, four Antarctic and four Arctic air samples were investigated for the presence of Q1. In the Antarctic air samples, Q1 levels ranged from 0.7 to 0.9 fg/m(3). In Arctic air samples, however, Q1 was below the detection limit (<0.06 fg/m(3) or 60 ag/m(3)). We also report on high Q1 levels in selected human milk samples (12-230 microg/kg lipid) and, therefore, suggested that the unknown Q1 is an environmental compound whose origin and distribution should be investigated in detail. Our data confirm that Q1 is a bioaccumulative natural organochlorine product. Detection of a highly chlorinated natural organochlorine compound in air and human milk is novel.