某新建苯乙烯项目职业病危害预评价

目的 识别和分析该项目在生产过程、劳动过程和生产环境中可能存在的职业病危害因素及其种类,评估其产生的部位、强度以及可能造成的职业病危害及其程度,论证建设项目可行性研究报告中涉及职业卫生篇章的深度及职业病危害防护措施的可行性、有效性、合理性.方法 选择与本项目类似的工程作为类比项目,采用类比调查法和经验法进行评价.结果 本项目生产过程中可能产生苯、甲苯、乙苯、苯乙烯、噪声等职业病危害因素,属严重职业病危害项目.工程选址、总体布局、采光与照明等符合国家有关规定,具有较完善的职业危害管理措施,装置现场职业病危害防护设施及应急事故处理设施有待完善.结论 本项目在生产过程中可能产生的职业病危害是可以预防的,从职业卫生角度分析本项目是可行的.     

空气污染与儿童呼吸系统患病率的相关分析

 在流行病学调查和空气污染物监测的基础上，研究讨论了儿童呼吸系统患病率与空气污染之间的相关关系，结果表明，空气中细颗粒物（PM_2.5）和可吸入颗粒物（PM₁₀）与儿童呼吸系统患病率呈线性正相关关系，其影响比SO₂、Nox更密切．哮喘明显受颗粒物、SO₂、Nox的综合作用的影响．未感冒咳嗽发生率明显受细颗粒物和Nox污染综合作用的影响．     

医院传染病污水处理技术探讨

以杭州市第六人民医院的污水处理设施为例，阐述了医院传染病污水处理技术的基本思路，并进而探讨了其消毒参数选择和处理的经济性，总结了还存在的问题及解决途径。     

机动车排出物对人体健康危害的研究

运用基因、ＤＮＡ、染色体，细胞和整个动物为终点的远期危害测试系统，对各类机动车排出尾气的有机提取物的致突变性及潜在致癌性进行了评估，同时运用流行病学方法对接触人群进行调查，结果表明：（１）柴油车，助动车的颗粒有机提取物包含１００多种化学物，（２）Ａｍｅｓ、ＵＤＳ微核及ＳＨＥ细胞恶性转化试验为阳性结果，具有突变性及致癌性。（３）它们能使人胚细胞形成转化灶并发现其中的ｃ－ｍｙｃ，ｐ２１及ｂｃｌ－２表达     

重庆酸沉降物对小学生肺通气功能影响的探讨

本文选择重庆市酸沉降物不同污染水平的三个地区,7～12岁小学生共计1081人,进行肺通气功能测定,共9项指标(FVC、FEV_1、FEV_1％、PEFR、MMEF、FVC％、V_(75)、V_(50)和V_(25))。结果发现10岁女小学生全部指标均显示出污染地区明显低于相对清洁区。尤以V_(50)和V_(25)更敏感(P<0.001)。本调查与攀枝花和辽宁两地区10岁女小学生部分肺通气功能进行比较,发现FVC、FEV_1和PEFR值重庆相对清洁区和污染区均比两地区低。特别是V_(50)和V_(25)的值低1～2倍。     

A study on Se application for improving the soil in the environment at lower Se level

A result that application of sodium selenite or fly ash to some of soilin loess plateau can increase Se content in wheat grain has been demonstrated by the pot and field experiments, and added Se in soil can last its availability for 3 years. So this is a good measure for improving the low Se soils and preventing the Kaschin-Beck disease.     

Prenatal diagnosis of chronic granulomatous disease (CGD) in four high risk male fetuses

Prenatal diagnosis of chronic granulomatous disease (CGD) was performed in four male high risk fetuses. The male sex was previously determined by an amniotic cell karyotype. Three kinds of test were performed on fetal blood obtained by umbilical venous puncture under fetoscopy at the 20th gestational week: nitroblue tetrazolium reduction (NBT) cytochemical test with phorbol myristate acetate (PMA) as activator; luminol enhanced chemiluminescence with activation by serum opsonized zymosan (STZ) or PMA; superoxide anion (0) production by measurement of the superoxide dismutase inhibitable reduction of cytochrome c with PMA as activator. Results were compared to those obtained in six fetuses investigated for other inherited diseases. In one case, absence of granulocyte defects was confirmed at birth. In three other cases, the tests showed deficient metabolic oxidative granulocytes. The pregnancy was terminated and the CGD diagnosis was confirmed on the products of abortion. The use of three different techniques performed on whole blood for CGD prenatal diagnosis is recommended instead of a single isolated test to ensure a higher confidence in the diagnosis.     

Fetal translocation between chromosomes 2, 18, and 21 resolved by fish

An apparently balanced t(2q;21q) translocation was discovered in fetal blood and amniocytes of a 22-week fetus, monitored because of ultrasonographic evidence of a heart disease. FISH (fluorescence in situ hybridization) analysis disclosed a complex translocation between chromosomes 2q, 18q, and 21q, which was inherited from the healthy mother. This observation corroborates the usefulness of molecular cytogenetic techniques in raising the quality of prenatal diagnosis and detecting subtle rearrangements not resolved by standard cytogenetics.     

The epidemic characteristics of Kaschin-Beck disease (KBD) in different eco-environments

Epidemiological survey of 573 families, clinical examination of 2593 persons, and X-ray examination of 1136 persons (in 16 typical endemic villages) were conducted, based on the classification of endemiology for KBD disease areas, i.e, mountain type, loess plateau type, plateau type, and flatlands type. It was revealed that the KBD disease areas exhibited the regular pattern of corming-into-being, development and passing-away and the characteristics of growth and decline. Further, it was found clinically that the disease areas may be divided into 4 types, i.e., recent onset, developing, stable, and historical. This division is simple and easy, practical, scientific, and reliable and can be applied by medical personnel at different levels.