Solvent‐Cast Polymeric Films from Pectin and Eudragit® NE 30D for Transdermal Drug Delivery Systems

Journal of Polymers and the Environment - In this study, solvent-cast polymeric films containing ionic liquid lidocaine/aspirin for transdermal patches were developed. Solvent-cast polymeric films...     

Formulation and Evaluation of Matrix Type Transdermal Patch Containing Silver Nanoparticles

This research aimed to prepare the silver nanoparticles (AgNPs)-loaded antimicrobial wound dressing patch using ethyl cellulose as a matrix membrane and diethyl phthalate as a plasticizer. The polymer suspension was homogeneously mixed with plasticizer, and then added to the colloidal AgNPs suspension. This mixture was poured into Petri dish and subsequently dried in a hot air oven at 80?±?2 °C for 10 h. The minimum inhibition concentration of the colloidal AgNPs suspension was 2.5 µg/ml. The AgNPs-loaded antimicrobial wound dressing patch was evaluated for physical properties by differential scanning calorimeter, X-ray diffraction, scanning electron microscope, and in vitro study. The antimicrobial wound dressing patch did not exhibit any interaction between the matrix membrane and AgNPs. The AgNPs were evenly dispersed in the patch. The patch could control the release of silver at 102.98?±?4.11% over 12 h. Although the AgNPs-loaded antimicrobial wound dressing patches can be easily prepared by the simple method, in future studies antimicrobial wound dressing patch will be developed by employing different types of film forming agents.     

Formulation Design of Oral Strip-Films Based on PVA/PVP Polymer Blends for Nicotine Delivery

Journal of Polymers and the Environment - This work prepared oral strip-film for nicotine delivery using polyvinyl alcohol and polyvinylpyrrolidone as polymeric film and glycerin as a plasticizer....