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Enhanced concentrations of Fe, Zn, Mn, Pb, Cu, Cd and total hydrocarbons (THC) determined in fish samples from the Cross River system, Nigeria have been associated with clinical defects (nausea, headache, hepatitis, body rashes) observed in coastal residents who are the major consumers of the fish species. Fish samples were collected from ten locations with varying degrees of exposure to human activities. Heavy metal concentrations in fish followed the sequence: Fe>Zn>Mn>Pb>Cu>Cd with the highest concentration of 243 g/g (Fe) wet weight occurring in Tympanotonus sp. Fe levels were significantly (P<0.001) higher than other metals analysed. The sequence in total hydrocarbon concentrations according to fish species was in the order of O. niloticus (55.1 g/g) > E. fimbriata > P. elongatus > Portonus sp. > C. nigrodigitatus > Tympanotonus sp. Generally, the demersal species showed a marked potential for tolerating high levels of heavy metals while the pelagic species showed preference for the accumulation of hydrocarbons. The degree of contamination depended on pollutant type, fish species, sampling location, trophic level and their mode of feeding. The persistent accumulation and tolerable potential of Tympanotonus, Portonus and P. elongatus suggest that they might be effectively utilized as self-integrating indicators for time-series monitoring of the rate of recovery of the impacted ecosystem by heavy metals. Possible sources of pollutant include leachates from municipal dumps, used crankcase oils from fluvial discharges (mechanic workshops) and occasional oil spills.  相似文献   
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We describe two newborn sisters who presented in the third trimester with diminished fetal movements and skin edema, but with no other signs of hydrops fetalis. Within hours of birth, both developed profound lactic acidemia, followed by multi-organ failure. In muscle mitochondria, the activity of all enzymatic complexes that contain mitochondrial DNA (mtDNA)-encoded subunits was markedly decreased. Southern blot analysis revealed a profound reduction in the mtDNA/nuclear DNA ratio, implying mtDNA depletion. The prenatal identification of skin edema in two patients with mtDNA depletion, and its absence in a healthy sibling, suggest that skin edema should be regarded as a novel manifestation of mtDNA depletion. This finding shows that mtDNA depletion can present prenatally and, consequently, may aid the clinician in making a diagnosis, prenatally, of this genetic defect. Copyright © 2002 John Wiley & Sons, Ltd.  相似文献   
3.
Journal of Polymers and the Environment - Cellulose nanopaper (CNP) is a new potential candidate for flexible biopolymer substrate made of nanocellulose (NC). We systematically studied the effect...  相似文献   
4.
Environmental Science and Pollution Research - Aquaculture has emerged as one of the world’s fastest-growing food industries in recent years, helping food security and boosting global...  相似文献   
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