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1.
Pure fetal blood has been aspirated in utero from the umbilical vein near the placental insertion of the cord using a twenty gauge needle under ultrasound guidance. Sixty-six samples were taken on 63 pregnancies between 17 and 32 weeks of gestation. One to two millilitres of blood can be obtained easily without amniotic fluid dilution or contamination by maternal blood, as confirmed by the measurements of the mean corpuscular volume, the histogram distribution of the red blood cells and the hematocrit. In all cases the Kleihauer test and isoelectrofocusing of the hemoglobins were performed. Coagulation factors were also studied in 60 cases. In 17 cases a medical abortion was voluntarily induced after the procedure, and the follow-up was normal during the observation period after sampling. In the other cases, pregnancies have continued normally and twelve healthy babies have already been born. 相似文献
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F. Daffos F. Forestier J. Mac Aleese C. Aufrant L. Mandelbrot E. A. Cabanis M. T. Iba-Zizen J. M. Alfonso J. Tamraz 《黑龙江环境通报》1988,8(4):311-314
Fetal magnetic resonance (MR) imaging was performed at 33 weeks of gestation for investigation of a posterior fossa abnormality found at ultrasound screening. Fetal movements were abolished by vecuronium injected under ultrasound guidance into the umbilical vein. MR images showed atrophy of the left cerebellar lobe with cisternal dilatation. These were confirmed postnatally by CT scan. 相似文献
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Ph. Labrune MD J. C. Pons M. Khalil V. Mirlesse M. C. Imbert M. Odièvre F. Daffos G. Tchernia R. Frydman 《黑龙江环境通报》1993,13(6):463-466
Three fetuses with TAR (thrombocytopenia with absent radii) or TAR variant syndrome were found to be thrombocytopenic during the third trimester of the pregnancy. These findings indicate that fetal blood sampling, besides ultrasonography, skeletal radiographs, or even fetoscopy, may indeed contribute to the prenatal diagnosis of TAR syndrome, and thus may help in differentiating TAR syndrome from other syndromes with malformations of the upper limbs. 相似文献
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Prenatal diagnosis has been performed on umbilical cord blood of an 18 weeks fetus of heterozygous triosephosphate isomerase (TPI) deficient parents. After excluding maternal blood contamination, TPI activity was measured and found to be 60 per cent of the normal mean whereas the value of glucose-6-phosphate dehydrogenase activity was in the normal range of fetal blood. In addition, the analysis of the characteristics of fetal TPI, i.e. Km measurements for glyceraldehyde-3-phosphate, heat stability tests and electrophoretic studies, did not show any evidence of a special form of TPI in fetal blood. These results were consistent with the heterozygous state and were confirmed at birth. 相似文献
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Kouadio Affian Marc Robin Mohamed Maanan Bruno Digbehi Eric Valère Djagoua Fernand Kouamé 《Environmental monitoring and assessment》2009,159(1-4):531-541
Surface sediments throughout Ebrié lagoon, Côte d’Ivoire were collected in 2001 and analyzed for their heavy metal and polycyclic aromatic hydrocarbons (PAH) contaminant content. Geochemical maps of heavy metals (Cd, Cu, Zn, Fe, and Mn) in the surface sediment were produced based on geographical information system (GIS) technology. Heavy metals and PAH were detected at high concentration and provide evidence for several anthropogenic inputs to the lagoon. A significant spatial relationship was found for Fe, Zn, and Cu in the sediment using a GIS-based analysis, suggesting that these metal contaminants in the sediments of the Biétri bay had common sources. 相似文献
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Claire Laberge-Nadeau François Bellavance Stéphane Messier Lyne Vézina Fernand PichetteAuthor vitae 《Journal of Safety Research》2009,40(6):427-435
Problem
Side impacts are a serious automotive injury problem; they represent about 30% of all fatalities for passenger vehicle occupants. This literature review focuses on occupant injuries resulting from real lateral collisions. It emphasizes the interaction between injury patterns and crash factors, taking into account type of injuries and their severity. It highlights what is known on the subject and suggests further studies.Method
We reviewed papers identified by searches in two electronic databases for the 1996-2009 publication period, and in specific journals and conference proceedings.Results
Studies on the Primary Direction of Force (PDOF) have revealed that fatal crashes occur most frequently when the PDOF is at 3 or 9 o'clock. The risk of serious injury is two to three times higher for the near-side occupant than for the far-side occupant. Head injuries predominate in oblique impacts and thoracic injuries in perpendicular ones. A few results are also reported on side airbag protection.Conclusions
This literature review presents an overall picture of the injuries caused by lateral collisions, though each of the papers or articles examined focuses mostly on some particular aspect of the problem. The incidence of specific injuries depends on the data source used. Very few population-based analyses of lateral collision injuries were found.Impact on industry
New studies are needed to evaluate new protective devices (e.g., lateral airbags, inflatable curtains). Without interfering with their care duties, Emergency Medical Technicians could be systematically trained to observe the collision's specific characteristics and to report all their relevant observations to the emergency physicians to increase the likelihood of prompt diagnosis and proper care. 相似文献9.
Patrick Hohlfeld Thi-Tan Dang K. Nahoul Fernand Daffos François Forestier 《黑龙江环境通报》1994,14(10):907-912
Normal levels of cancer-associated antigen (CA) 19-9, neurone-specific enolase (NSE), cancer-associated antigen (CA) 125, and mucin-like carcinoma-associated antigen (MCA) during pregnancy were determined in 87 mothers and fetuses, using a solid-phase sandwich enzyme immunoassay. CA 19-9 concentrations were higher in the fetuses, whereas the other three tumour-associated antigen levels were higher in the mothers. Only fetal NSE and MCA levels were positively correlated with those in maternal serum. Contrary to adult samples, no difference was demonstrated between male and female fetal levels of CA 125. MCA was the only maternal marker that increased significantly with gestational age between 20 and 34 weeks' pregnancy. 相似文献
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Bernard Guyot Anne Bazin Yvette Sole Christophe Julien Fernand Daffos François Forestier 《黑龙江环境通报》1988,8(7):485-493
We have used a Y-chromosome specific DNA probe in a controlled study to determine the presence of Y-chromosome material and to detect numerical abnormalities in uncultured amniotic fluid cells by fluorescent hybridization. Using this non-radioactive method, we correctly predicted fetal sex within 48 h in all but 3 of 54 cases and identified an XYY syndrome. The technique was previously tested with no false-positive or false-negative results on cultured interphase or metaphase nuclei of fetal fibroblasts and adult T-lymphocytes. Fluorescent in situ hybridization was applied to long-term fixed cytogenetic preparations up to 44 months old and was shown to be reliable. 相似文献