Die Kontrolle der Wanderung und Differenzierung von Neuralleistezellen durch die Extrazelluläre Matrix

Neural crest cells give rise to various essential tissues in vertebrates. Among these are the teeth, the ganglia of the peripheral nervous system, endocrine cells and pigment cells. Neural crest cells are actively migrating cells, but their migration needs to be stimulated by an appropriate extracellular matrix (ECM). In the present article the role of the epidermis and subepidermal ECM during the migration of neural crest cells and their differentiation into pigment cells in amphibian embryos will be considered. Furthermore, a new microcarrier technique will be presented with which the influence of natural ECM and various ECM components on the behavior and differentiation of neural crest derivatives can be investigated in amphibian embryos.     

Sicherheitsvorkehrungen bei Kernkraftwerken mit Druckwasserreaktoren und ihr Funktionsnachweis durch großtechnische Experimente,II

Analyses and experiments carried out during the last decade on the sequence and consequences of accidents in German pressurized water reactors have shown that the functioning capability of the safety systems is guaranteed for the case of the MCA, the maximum credible accident. For the case of core meltdown, simulation experiments have also made it evident that the consequences remain largely restricted to the plant proper.