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排序方式: 共有414条查询结果,搜索用时 15 毫秒
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Marc Trimborn Rolf-Dieter Wegner Holger Tönnies Nanette Sarioglu Matthias Albig Heidemarie Neitzel 《黑龙江环境通报》2006,26(3):273-276
We describe the first prenatally detected case of a small de novo interstitial duplication of chromosome 16q. This chromosomal aberration is extremely rare. Amniocentesis was indicated by advanced maternal age only. Ultrasound examinations of the foetus showed no abnormalities. Conventional and molecular cytogenetic analyses on cultured amniocytes by comparative genomic hybridisation (CGH) and fluorescence in situ hybridisation (FISH) using partial chromosome paints and a locus-specific YAC clone revealed a de novo direct duplication of the chromosomal region 16q11.2-q13 leading to a partial trisomy 16q (46,XX,dup(16)(q11.2q13)). There are only five postnatal reports of comparable duplications involving this chromosomal region. These patients presented with little or no associated dysmorphic features but with significant neurodevelopmental delay and severe behavioural problems. After genetic counselling, the parents opted for termination of pregnancy. Post-mortem examination showed slight facial dysmorphic signs, minor dysgenesis of the ovaries and an atypical outflow of the arteria thyroidea ima. Copyright © 2006 John Wiley & Sons, Ltd. 相似文献
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Bunge Michael Khknen Mika A. Rmisch Winfried Opel Matthias Vogler Susanne Walkow Fred Salkinoja-Salonen Mirja Lechner Ute 《Environmental science and pollution research international》2007,14(1):3-10
Background, Aims and Scope Sediments of the Spittelwasser creek are highly polluted with organic compounds and heavy metals due to the discharge of untreated
waste waters from the industrial region of Bitterfeld-Wolfen, Germany over the course of more than one century. However, relatively
few data have been published about the chloroorganic contamination of the sediment. This paper reports on the content of different
(chloro)organic compounds with special emphasis on polychlorinated dibenzo-p-dioxins and dibenzofurans (PCDD/F), and chlorobenzenes. Existing concepts for the remediation of Spittelwasser sediment include
the investigation of natural attenuation processes, which largely depend on the presence of an intact microbial food web.
In order to gain more insight in terms of biological activity, we analyzed the capacity of sediment microflora to degrade
organic matter by measuring the activities of extracellular hydrolytic enzymes involved in the biogeochemical cycling of carbon,
nitrogen, phosphorus and sulfur. Furthermore, the detection of physiologically active bacteria in the sediment, particularly
of those known for their capability to reductively dehalogenate organochlorine compounds, illustrates the potential for intrinsic
bioremediation processes.
Methods PCDD/F and chlorobenzenes were analyzed by gas chromatography(GC)/mass spectrometry and GC/flame ionization detection, respectively.
The activities of hydrolytic enzymes were determined from freshly sampled sediment layers using 4-methylumbelliferyl (MUF)
or 7-amino-4-methylcoumarin-conjugated model compounds and kinetic fluorescence measurements. Physiologically active bacteria
from different sediment layers were microscopically visualized by fluorescence in situ hybridization (FISH). Specific bacteria were identified by 16S rRNA gene amplification and sequencing.
Results and Discussion The PCDD/F congener profile was dominated by dibenzofurans. In addition, the presence of specific tetra and pentachlorinated
dibenzofurans supported the assumption that extensive magnesium production was one possible source for the high contamination.
A range of other chloroorganic compounds, including several isomers of chlorobenzenes, hexachlorocyclohexane and 1,1,1-trichloro-2,2-bis
(p-chloro-phenyl)ethane (DDT), was present in the sediment. Activities of extracellular hydrolytic enzymes showed a strong
decrease in those sediment layers that were characterized by high contents of absorbable organic halogen (AOX), indicating
disturbed organic matter decay. Interestingly, an abnormal increase of cellulolytic enzyme activities below the organochlorine-rich
layers was observed, possibly caused by residual cellulose from discharges of sulfite pulping wastes. FISH revealed physiologically
active bacteria in most sediment layers from the surface down to the depth of about 60 cm, including members of Desulfitobacterium (D.) and Sulfurospirillum. The presence of D. dehalogenans was confirmed by its partial 16S rRNA gene sequence.
Conclusions Results of chemical sediment analyses demonstrated high loads of organochlorine compounds, particularly of PCDD/F. Several
years after stopping the waste water discharge to Spittelwasser creek, this sediment remains a main source for pollution of
the downstream river system by way of the ongoing mobilization of sediment during high floods. As indicated by our enzyme
activity measurements, the decomposition potential for organic matter is low in organochlorine-rich sediment layers. In contrast,
the comparably higher enzyme activities in less organochlorine-polluted sediment layers as well as the presence of physiologically
active bacteria suggest a considerable potential for natural attenuation.
Recommendations and Perspectives From our data we strongly recommend to explore the degradative capacity of sediment microorganisms and the limits for in situ activity towards specific sediment pollutants in more detail. This will give a sound basis for the integration of bioremediation
approaches into general concepts to reduce the risk that permanently radiates from this highly contaminated sediment.
Submission Editor: Dr. Henner Hollert (Henner.Hollert@urz.uniheidelberg.de) 相似文献
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Jenny M. McCarthy Thomas Gumbricht Terence McCarthy Philip Frost Konrad Wessels Frank Seidel 《Ambio-人类环境杂志》2003,32(7):453-457
欧科范果三角洲地区泛滥范围年年在变化.这种变化与安哥拉高地集水区的区域性降水及当地降雨量有关.我们采用了1972~2000年的3000多幅卫星图像来描绘湿地的格局,其中从1985~2000年的图像几乎是NOAAAVHRR每日连续传送的,1972年以来的其它图像是从Landsat传感器上传下来的,其连续性次之.对AVHRR图像每10天为一期,用无监督分类方法分成陆地和水体.对LandsatTM和ERS2-ATSR数据进行分析的结果,与测算的淹没区域89%相吻合.结果显示欧科范果湿地近期30年期间的变化约在2450~11400km2之间. 相似文献
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Kuangxin Zhou Matthias Barjenbruch Christian Kabbe Goulven Inial Christian Remy 《环境科学学报(英文版)》2017,29(2):151-159
Phosphorus (P) is a limited resource, which can neither be synthesized nor substituted in its essential functions as nutrient. Currently explored and economically feasible global reserves may be depleted within generations. China is the largest phosphate fertilizer producing and consuming country in the world. China''s municipal wastewater contains up to 293,163 Mg year of phosphorus, which equals approximately 5.5% of the chemical fertilizer phosphorus consumed in China. Phosphorus in wastewater can be seen not only as a source of pollution to be reduced, but also as a limited resource to be recovered. Based upon existing phosphorus-recovery technologies and the current wastewater infrastructure in China, three options for phosphorus recovery from sewage sludge, sludge ash and the fertilizer industry were analyzed according to the specific conditions in China. 相似文献
10.
Michael Gebhardt Markus Ess Sascha Weikert Wolfgang Knapp Konrad Wegener 《Journal of Manufacturing Processes》2013,15(4):452-459
Thermal errors of machine tools are one of the major sources of inaccuracy. Therefore, the reduction of temperature induced deviations or the compensation of the resulting tool center point (TCP) errors have been of strong interest to the manufacturing industry for a couple of years. Up to now, the observation of the environment, the main spindle, the linear axes and the machine bed were in the focus of research, but with the rising demand for 5-axis machine tools and the increasing requirements regarding their accuracy, the analysis of the thermal behavior of rotary axes becomes more and more important. This paper gives an overview of corresponding thermal measurements of machine tools. The thermal behavior of rotary and swiveling axes is analyzed in detail. A simulation model and an approach for a phenomenological compensation of the TCP error are introduced and verified by measurements. 相似文献