The relationship between microbial carbon and the resource quality of soil carbon

The biological health of soil is an important aspect of soil quality because of the many critical functions performed by organisms in soil. Various indicators of soil quality have been proposed, but measurements of microbial biomass are most commonly used. During decomposition of plant residues in soil the relative intensities of the O-alkyl-C signal decreases and the alkyl-C signal increases in nuclear magnetic resonance (NMR) spectra. This leads to the suggestion that the alkyl-C to O-alkyl-C ratio of a soil may indicate the degree of decomposition. Consequently, the overall resource quality of soil C as a substrate for heterotrophic microorganisms may be inversely related to the alkyl-C to O-alkyl-C ratio. Our hypothesis is that a relationship exists between the size of the soil microbial community (microbial biomass) and the quality of soil carbon as a resource for microorganisms. New data have been combined with previously published data to show that there was a significant, negative correlation between the biomass C to total C (Cmic, to Corg) ratio and the alkyl-C to O-alkyl-C ratio (p < 0.01), which supports our hypothesis.     

Secondary metabolism — evolution and function: Products or processes?

Summary The distinguishing characteristics of secondary metabolism and its associated metabolites are outlined. Current theories relating to the function of secondary metabolism in plants and micro-organisms are enumerated and the view that consideration of the processes rather than the products may best explain the origins of secondary metabolism is discussed.     

46,XY/47,XY,+ 17p+ mosaicism in amniocytes associated with fetal abnormalities despite normal fetal blood karyotype

46,XY/47,XY, + 17p + mosaicism was found in two primary amniotic fluid cultures (AFCs). Fetal blood karyotype was normal, but ultrasonography revealed Dandy-Walker malformation and bilateral choroid plexus cysts. Following termination of pregnancy, fetal examination revealed post-axial polydactyly and neuroblastoma-in-situ affecting both adrenals in addition to the cerebellar abnormalities. Mosaicism for the aberrant cell line was confirmed in all fetal tissues sampled and in the placenta.     

Improved direct molecular diagnosis and rapid fetal sexing

Adaptations of the techniques of modern molecular biology to prenatal diagnosis has opened new avenues for the detection of genetic diseases. We have taken advantage of the rapid adhesion of colony forming cells in cultured amniotic fluid samples to develop an improved method for molecular diagnosis. By employing the cell adherence regime sickle cell diagnosis using Mst II can be undertaken directly. In addition, hybridization with a cloned repetitive sequence that is of Y origin and has limited autosomal homology permits rapid fetal sexing in 3 to 4 days without compromising conventional cytogenetic or biochemical analysis. This combination of techniques provides a useful adjunct to convential prenatal genetic diagnosis in the second trimester.     

Examination of fetuses after induced abortion for fetal abnormality—a follow-up study

In the North-Western Region we offer a service to examine fetuses aborted after the diagnosis of fetal abnormalities. Many obstetricians use this service. We examined 343 mid-trimester fetuses over the last 5 years: 215 following an abnormal scan and 128 abnormal amniotic fluid or villus findings. When necessary, investigations were performed. A post-mortem examination was always required. As a result of fetal investigation, the scan diagnosis was modified or refined in 91 cases (42·3 per cent). In three of these cases, no fetal abnormality was found. For the fetuses diagnosed as abnormal by amniocentesis or chorionic villus biopsy, in one (0·8 per cent) the pre-termination diagnosis was not confirmed. The results were similar to those of our previous 5-year study except (a) diagnosis of neural tube defects was rarely based on amniocentesis in the present study (2/62, 3·2 per cent) compared with the previous one (32/103, 31 per cent), and (b) renal abnormalities were more often diagnosed in the pre-termination scan in the present study. We conclude that the examination of aborted mid-trimester fetuses by dysmorphologists continues to improve diagnosis, allowing more accurate genetic counselling for the families.     

Access and Local Government Research: Methodological Reflections

This methodological paper draws on research from Australia to examine the question of gaining access to local governments in undertaking work on natural resource management. It is argued that a range of macro-level changes have impacted on the local government sector in Australia, and these changes have rendered access problematic for researchers. These changes include an expansion of local government roles, an increase in financial pressure within the sector, a proliferation of audit measures across local governments and a low level of respect amongst local government personnel for academics and academic work. The paper concludes by identifying the reasons why understanding access in qualitative research on local government and environmental sustainability is important.     

Why employers spend money on employee health: Interviews with occupational health and safety professionals from British Industry

ObjectivesTo better understand the information that is used in business cases for employee health activities.MethodsInterviews with 18 occupational health and safety professionals at major organisations in the UK were conducted to explore attitudes, motivations, behaviours and information needs about employee health investment.ResultsThe occupational health and safety professionals interviewed for this study have described how employee health issues are discussed in their organisations. Ethical arguments about it being the ‘right thing to do’ are common and are believed to have impact. Unsurprisingly legal compliance is stated to be the driver of most employee health activity. Higher-level activities and resource do require a business case. It is suggested that currently business cases for employee health are often not overly empirical, with more intuitive arguments appealing to people management issues, notions of corporate reputation and alignment with business objectives. Data on benchmarking and some kind of return-on-investment assessment are normally required. Data on cost of illness (mostly expressed via sickness absence), direct health expenditure per employee and insurance premiums are also used. These data are mostly captured by existing sources and procedural systems, although sickness absence data especially is often thought to be unreliable. Data on staff retention and productivity were considered relevant but not currently used or analysed by this sample. There was support for the notion that more robust empirical business cases may help overcome some of the barriers that were identified, for example where costs are more quantifiable than benefits.ConclusionsThere is scope to make significant improvements to the business case for employee health investments in UK organisations through better measurement of impact on productivity and reputation risk and greater business-aligned communication by health professionals. More empirical business cases that meet the needs of decision-makers are more likely to attract investment into employee health activities.     

Access and Local Government Research: Methodological Reflections

Abstract

This methodological paper draws on research from Australia to examine the question of gaining access to local governments in undertaking work on natural resource management. It is argued that a range of macro-level changes have impacted on the local government sector in Australia, and these changes have rendered access problematic for researchers. These changes include an expansion of local government roles, an increase in financial pressure within the sector, a proliferation of audit measures across local governments and a low level of respect amongst local government personnel for academics and academic work. The paper concludes by identifying the reasons why understanding access in qualitative research on local government and environmental sustainability is important.     

Occupant interactions with self-closing fire doors in private dwellings

Prevention measures to reduce deaths and injuries due to domestic fires have included the provision of self-closing fire doors within dwellings. Such an approach however, is reliant on a behavioural response on behalf of the occupier(s). This research examined occupier behaviour in relation to self-closing fire doors. Forty semi-structured interviews were conducted with individuals inhabiting a new home. In all of the properties with self-closing fire doors, the occupants reported interfering with the self-closing mechanism of the doors. A quantitative survey was subsequently undertaken to obtain frequency data. In the majority of dwellings with fire doors occupiers reported propping these open in some way, or removing the self-closing mechanism from the door. The accounts suggest that, for fire doors to be an effective safety measure within dwellings, a greater emphasis needs to be placed on encouraging occupiers to adopt safe practices in relation to fire doors. Alternatively, other measures will need to be found to address the fire risk.     

The Potential Role for NELUP in Strategic Land Use Planning

The paper comments and speculates on the potential role for the NERC/ ESRC Land-use Modelling Programme in strategic land-use planning.