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Amicarelli Andrea Alessandrini Stefano Agate Giordano Ferrero Enrico Pirovano Guido Tinarelli Gianni Luigi Trini Castelli Silvia 《Environmental Fluid Mechanics》2021,21(2):433-463
Environmental Fluid Mechanics - A 3D dry deposition scheme for particulate matter (PM) is presented as a Free-Libre and Open-Source Software (FOSS) library, DePaSITIA (RSE SpA). This combines some... 相似文献
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Bioaccumulation models take various elimination and uptake processes into account, estimating rates from chemical lipophilicity, expressed as the octanol-water partition ratio (Kow). Here, we focussed on metabolism, which transforms parent compounds into usually more polar metabolites, thus enhancing elimination. The aim of this study was to quantify the change in lipophilicity of relevant organic pollutants undergoing various biotransformation reactions in mammals. We considered oxidation reactions catalyzed by three enzyme groups: cytochrome P450 (CYP), alcohol dehydrogenase (ADH), and aldehyde dehydrogenase (ALDH). Estimated log Kow values of a selected dataset of parent compounds were compared with the log Kow of their first metabolites. The log Kow decreased by a factor that varies between 0 and −2, depending on the metabolic pathway. For reactions mediated by CYP, the decrease in Kow was one order of magnitude for hydroxylated and epoxidated compounds and two orders of magnitude for dihydroxylated and sulphoxidated xenobiotics. On the other hand, no significant change in lipophilicity was observed for compounds N-hydroxylated by CYP and for alcohols and aldehydes metabolized by ADH and ALDH. These trends could be anticipated by the calculus method of log Kow. Yet, they were validated using experimental log Kow values, when available. These relationships estimate the extent to which the elimination of pollutants is increased by biotransformation. Thus, the quantification of the Kow reduction can be considered as a first necessary step in an alternative approach to anticipate biotransformation rates, which are hard to estimate with existing methods. 相似文献
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To develop sound air quality plans, regional authorities should have instruments that link the complex behaviour of pollutants both in time and space with costs of emission reduction. The problem is particularly important for ground level ozone which forms kilometres away, hours later from the emission of its precursors. To approach this problem, a method (1) to identify local pollutant-precursor models on the basis of results from a large photochemical model (CALGRID), (2) to integrate them in a multi-objective mathematical program, together with an estimate of the emission reduction costs, is suggested. The method has been used to assess action priorities in Lombardy (Northern Italy). This area, characterised by a complex terrain, high urban and industrial emissions and a dense road network is often affected by severe photochemical pollution episodes during summer. 相似文献
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E. Angelino M. Bedogni C. Carnevale G. Finzi E. Minguzzi E. Peroni C. Pertot G. Pirovano M. Volta 《Environmental Modeling and Assessment》2008,13(3):401-413
Within the framework of CityDelta open model inter-comparison exercise, two different atmospheric chemical transport models,
comprehensive air quality model with extension and transport chemical aerosol model, have been applied over a domain centred
on Milan (North of Italy) as a result of a cooperation of five Italian groups. The two models have shared the same input fields
for yearly PM10 simulations. The paper illustrates the analysis of the particulate matter-simulated concentrations and the
comparison with the available experimental data. 相似文献
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