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Immunotoxicological effects of cypermethrin and their reversal by curcumin following oral administration were evaluated in rats. Mature male Wistar rats were orally administered cypermethrin (25?mg?kg?1 body wt), curcumin (100?mg?kg?1 body wt) or both daily for 4 weeks. At the end of fourth week, hematological, serum biochemical, and immunological parameters were studied. Subchronic exposure to cypermethrin significantly reduced body weight, total leukocyte count, lymphocyte count, serum total protein, serum albumin, serum globulin, antibody titer against sheep red blood cells, and cell-mediated immunity. Concomitant curcumin administration restored the changes in the body weight, hematological parameters, and serum biochemical indices and significantly increased the antibody titer, and cell mediated immunity. These results suggest that concurrent curcumin treatment has a beneficial role in mitigating immunotoxicological and other adverse effects of cypermethrin. 相似文献
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Tamilvanan Ayyasamy Balamurugan Kulendran Ashok Bragadeshwaran Selvakumar Pandiaraj Dhamotharan Subbaiyan Bharathiraja Moorthy Karthickeyan Viswanathan 《Environmental science and pollution research international》2021,28(26):33880-33898
Environmental Science and Pollution Research - The present experimental investigation is conducted to examine the working characteristics of compression ignition (CI) engine using oxygenated... 相似文献
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