排序方式: 共有4条查询结果,搜索用时 0 毫秒
1
1.
D Bussolaro F Filipak Neto A Glinski H Roche IC Guiloski M Mela HC Silva de Assis CA Oliveira Ribeiro 《Journal of environmental monitoring : JEM》2012,14(8):2154-2163
Few studies have investigated the bioaccumulation of persistent organic pollutants (POPs) in Brazilian native freshwater fish. In order to evaluate the bioavailability, potential risk to human exposure and the effects of POPs in the fish Hypostomus commersoni, muscle and liver samples of thirteen specimens were collected in a lake located in the city of Ponta Grossa (Parana State, Southern Brazil). Also, the liver and gills were considered for histopathological studies, and oxidative stress was investigated in the liver. Expressive concentrations of POPs were observed in the liver and muscle, with a total of 427 ± 78.7 and 69.2 ± 18.1 ng g(-1) dry weights of polychlorinated biphenyls (PCBs), respectively. Negative correlations between the concentration of several POPs and glutathione S-transferase and glucose-6-phosphate dehydrogenase were found. Otherwise, the cholinesterase activity in the muscle and brain presented positive correlations with the concentration of POPs. The hepatic bioaccumulation of some banned pesticides like aldrin, dieldrin and DDT was associated with various histopathological findings in the liver and gills. Necrotic areas, fibrosis, leukocyte infiltration, and the absence of macrophage centers were observed in the liver, indicating both chronic exposure and immunological suppression. Neoplasic changes were observed in the gills, confirming the carcinogenic potential reported for some of the investigated pollutants. The current work was the first to study the bioaccumulation of POPs in H. commersoni, an important species in ecological aspects and as a vehicle to human exposure to PCBs and organochlorine pesticides (OCPs). 相似文献
2.
Izonete Cristina Guiloski Stéfani Cibele Rossi Cesar Aparecido da Silva Helena Cristina Silva de Assis 《Journal of environmental science and health. Part. B》2013,48(4):272-277
This study was undertaken to investigate the effects of sublethal concentration of three different classes of insecticides (carbamate, organophosphate, and pyrethroid compounds) on the freshwater fish Corydoras paleatus. For this purpose, fish were exposed for 96 hours to commercial pesticides. Different biomarkers were analyzed as levels of lipid peroxidation (LPO), piscine micronucleus test, and enzymatic activities of catalase (CAT), glutathione S-transferase (GST), and acetylcholinesterase (AChE). The brain AChE was inhibited with carbaryl and methyl parathion, but no inhibition was observed with deltamethrin. The insecticides did not cause oxidative stress or genotoxic effects at the tested concentrations. Further studies are needed to elucidate the biotransformation of Corydoras paleatus insecticides and a possible resistance mechanism. 相似文献
3.
Lima Luíza Siqueira Galiciolli Maria Eduarda Andrade Pereira Meire Ellen Felisbino Karoline Machado-Souza Cleber de Oliveira Cláudia Sirlene Guiloski Izonete Cristina 《Environmental science and pollution research international》2022,29(29):43435-43447
Environmental Science and Pollution Research - As well as a lead-related environmental factor, genetic factors could also corroborate important changes in intelligence quotient (IQ) through... 相似文献
4.
Dayana Moscardi dos Santos Gustavo Souza Santos Marta Margarete Cestari Ciro Alberto de Oliveira Ribeiro Helena Cristina Silva de Assis Flavia Yamamoto Izonete Cristina Guiloski Mary Rosa Rodrigues de Marchi Rosalinda Carmela Montone 《Environmental science and pollution research international》2014,21(4):3166-3174
The toxicity of butyltin compounds (BTs), mainly tributyltin (TBT), has been reported in different organisms. However, such an analysis in fish after field exposure with reference to the related biomarkers has not been commonly observed in the literature. This study presents the uptake of BTs in the liver of a neotropical marine catfish Cathorops spixii in Paranagua Bay, an important estuarine system located in southern Brazil. Two different areas, close to and distant from the harbor, were used for chemical analysis evaluation of hepatotoxicity through genetic, enzymatic, and histopathological biomarkers. The presence of polycyclic aromatic hydrocarbons in bile was also considered as a biomarker. The results showed a significant relationship between TBT levels and the inhibition of biotransformation enzymes and high occurrence of melanomacrophages in fish collected close to the harbor site. These effects were linked to the absence of TBT metabolites in the liver. In the second site, the presence of DBT was associated with an increase in EROD and GST activity. The larger amount of DNA damage as well as the highest oxidative stress was noted in fish from the less TBT-polluted area, where DBT and bile PAHs occurred. These findings showed different impact levels due to or increased by the chronic exposure of biota to BTs. 相似文献
1