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1.
The outcome of the pregnancy following (a) a mid-trimester termination of pregnancy (TOP) for fetal neural tube defect (NTD) (77 women=group 1); (b) mid-trimester TOP for fetal Down's syndrome (13 women=group 2); (c) delivery of a baby with NTD (119 women=group 3) was studied. The prenatal fetal loss was relatively high in all groups. In group 1 it was similar to that found in other studies after first trimester TOP, in group 2 it was associated with advanced maternal age and the unexpected finding in group 3 was not attributable to advanced maternal age. It is suggested that a previous NTD per se might increase the risk of fetal loss in the next pregnancy. A previous mid-trimester TOP for NTD was not associated with an increase in premature labour, small for dates babies or congenital abnormality in the next pregnancy, but there was a slight increase in the number of babies weighing less than 2500 g.  相似文献   
2.
Northern Ontario’s Ring of Fire/Wawangajing controversy constitutes a complex site of debate about the risks and benefits of mining in an area of major ecological significance that is also the ancestral territory of nine First Nation communities. This paper investigates the rhetorical alignments and divergences in public calls by Matawa First Nations tribal council and the Ontario Wildlands League for stronger environmental assessment of mining projects than that favoured by the Canadian government. Tracing the terminologies each group uses to describe the affected region and its inhabitants in its activist rhetoric about EA offers insight into the contingent, shifting ways in which wilderness advocacy and Indigenous justice discourses may speak together yet distinctly within contemporary environmental-natural resource disputes.  相似文献   
3.
This case study of an NGO's response to a food crisis due to crop failure focuses on the extent of active community participation at each stage of the project. With the current debate on the relationship between relief and development, and in particular the focus on encouraging more active community participation in relief responses, this study has relevance both in the Ethiopian context and beyond.
In this example the participation process was greatly facilitated by the prior relationship between the international NGO and the communities, and also by the high level of staff input into the project. Where resources or conditions are less favourable, as might be the case in similar responses by local NGOs or government agencies, the paper suggests that the participatory approach can be adapted or partially implemented and still result in a more effective and locally relevant operation.  相似文献   
4.
Nanotechnology globally represents a new direction within scientific development, where the atomic and electronic properties of molecules are used in a unique fashion to produce and construct new and exotic materials and products. Fullerenes (Bucky balls, C60) constitute a particular group within the field of nanotechnology. Fullerenes find applications in medicine, industrial chemistry and electronics. However, there are several unanswered questions about fullerenes and their toxicological properties. Most toxicological studies on fullerenes evolve around the in vitro and in vivo aspects of pristine C60 along with chemically modified C60 molecules. We reviewed toxicology reports on C60. We bring a critical and challenging evaluation of the electronic and quantum properties of C60 molecules in context with the implications on cellular factors and metabolites. The evaluation shows that the reactivity and quantum chemical properties of C60 can have unexpected effects in the cell, by principally absorbing metabolites, such as OH? and H+ ions and alter its reactivity. We thus challenge the present view of C60 solely based on empirical studies, based on the electronic properties of C60 that vary considerably with their size and reaction path. A further example of this is the absorption of divalent zinc ions, which shows an increase in reactivity of the C60 that presents an important pattern of chemical state, reactivity and toxicological potential. The results evaluate the toxicological potential of C60 from a different angle than conventional, by applying a blend of critical review of the findings on C60 toxicity, their chemical and electronic properties.  相似文献   
5.
This synthesis article joins the authors of the special issue “Gender perspectives in resilience, vulnerability and adaptation to global environmental change” in a common reflective dialogue about the main contributions of their papers. In sum, here we reflect on links between gender and feminist approaches to research in adaptation and resilience in global environmental change (GEC). The main theoretical contributions of this special issue are threefold: emphasizing the relevance of power relations in feminist political ecology, bringing the livelihood and intersectionality approaches into GEC, and linking resilience theories and critical feminist research. Empirical insights on key debates in GEC studies are also highlighted from the nine cases analysed, from Europe, the Americas, Asia, Africa and the Pacific. Further, the special issue also contributes to broaden the gender approach in adaptation to GEC by incorporating research sites in the Global North alongside sites from the Global South. This paper examines and compares the main approaches adopted (e.g. qualitative or mixed methods) and the methodological challenges that derive from intersectional perspectives. Finally, key messages for policy agendas and further research are drawn from the common reflection.  相似文献   
6.
Data-logging devices are commonly used to study the foraging behaviour of individual seabirds. Such studies need to examine the potential effects of using devices on instrumented individuals, not only for ethical reasons but also to ensure the validity of data gathered. We studied the effects of two types of device (time-depth recorder and global positioning system) on little penguins (Eudyptula minor) during the 2010 and 2011 breeding season at Oamaru, New Zealand. Mixed-effect models were used to test for effects of devices by comparing changes in body weight, chick growth and breeding performance between instrumented and control individuals. We found no detectable effects of the attached devices on body weight change, hatching success, fledging success, chick growth parameters or adult survival. We conclude that it is possible to attach data-logging devices to adult little penguins for extended periods during the breeding season with minimal impacts.  相似文献   
7.
Development policy increasingly focuses on building capacities to respond to change (adaptation), and to drive change (innovation). Few studies, however, focus specifically on the social and gender differentiation of capacities to adapt and innovate. We address this gap using a qualitative study in three communities in Solomon Islands; a developing country, where rural livelihoods and well-being are tightly tied to agriculture and fisheries. We find the five dimensions of capacity to adapt and to innovate (i.e. assets, flexibility, learning, social organisation, agency) to be mutually dependant. For example, limits to education, physical mobility and agency meant that women and youth, particularly, felt it was difficult to establish relations with external agencies to access technical support or new information important for innovating or adapting. Willingness to bear risk and to challenge social norms hindered both women’s and men’s capacity to innovate, albeit to differing degrees. Our findings are of value to those aspiring for equitable improvements to well-being within dynamic and diverse social–ecological systems.  相似文献   
8.
9.
The new ACE2 (Altimeter Corrected Elevations 2) Global Digital Elevation Model (GDEM) which has recently been released aims to provide the most accurate GDEM to date. ACE2 was created by synergistically merging the SRTM and altimetry datasets. The comprehensive comparison carried out between the two datasets yielded a myriad of information, with the areas of disagreement providing as much valuable information as the areas of agreement. Analysis of the comparison dataset revealed that certain topographic features displayed consistent differences between the two datasets. The largest differences globally are present over the rainforests, particularly the two largest, around the Amazon and the Congo. The differences range between 10 m and 40 m; these differences can be attributed to the height of the rainforest canopy, as the SRTM returned height values from somewhere within the uppermost reaches of the vegetation whereas the altimeter was able to penetrate through and return true ground heights. The second major class of terrain feature to demonstrate coherent differences are desert regions; here, different deserts present different characteristics. The final area of interest is that of Wetlands; these are areas of special significance because even a slight misrepresentation of the heights can have wide ranging effects in modelling wetland areas. These examples illustrate the valuable additional information content gleaned from the synergistic global combination of the two datasets.  相似文献   
10.
Fetal growth restriction (FGR) is associated with threefold to fourfold increased risk of stillbirth. Identifying FGR, through its commonly used surrogate—the small-for-gestational-age (SGA, estimated fetal weight and/or abdominal circumference <10th centile) fetus—and instituting fetal surveillance and timely delivery decrease stillbirth risk. Methods available to clinicians for antenatal identification of SGA fetuses have surprisingly poor sensitivity. About 80% of cases remain undetected. Measuring the symphysis-fundal height detects only 20% of SGA fetuses, and even universal third trimester ultrasound detects, at best, 57% of those born SGA. There is an urgent need to find better ways to identify this at-risk cohort. This review summarises efforts to identify molecular biomarkers (proteins, metabolites, or ribonucleic acids) that could be used to better predict FGR. Most studies examining potential biomarkers to date have utilised case-control study designs without proceeding to validation in independent cohorts. To develop a robust test for FGR, large prospective studies are required with a priori validation plans and cohorts. Given that current clinical care detects 20% of SGA fetuses, even a screening test with ≥60% sensitivity at 90% specificity could be clinically useful, if developed. This may be an achievable aspiration. If discovered, such a test may decrease stillbirth.  相似文献   
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