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多级厌氧法处理螺旋霉素工业发酵菌渣效果的研究
引用本文:朱培,张建斌,李继安,邵雷,储炬,陈代杰.多级厌氧法处理螺旋霉素工业发酵菌渣效果的研究[J].环境工程学报,2014,8(2):703-708.
作者姓名:朱培  张建斌  李继安  邵雷  储炬  陈代杰
作者单位:1. 华东理工大学生物反应器工程国家重点实验室, 上海 200237;2. 上海医药工业研究院创新药物与制药工艺国家重点实验室, 上海 200040;2. 上海医药工业研究院创新药物与制药工艺国家重点实验室, 上海 200040;2. 上海医药工业研究院创新药物与制药工艺国家重点实验室, 上海 200040;2. 上海医药工业研究院创新药物与制药工艺国家重点实验室, 上海 200040;1. 华东理工大学生物反应器工程国家重点实验室, 上海 200237;3. 中国医药工业研究总院, 上海 200040
基金项目:国家“重大新药创制”科技重大专项资助项目(2012ZX09201101)
摘    要:通过自主设计的多级厌氧反应器系统来考察半连续处理螺旋霉素工业发酵菌渣的效果。该系统总反应体积为44 L,由4个11 L的升流式厌氧反应罐组成,罐体间采用串联方式连接。121 d的连续运行周期分为3个阶段,各阶段的有机负荷率分别为1.27、1.82和2.73 kg COD/(m3·d)。全过程中主要监测了各级罐体的产气量和螺旋霉素的降解。结果表明,多级厌氧反应器系统启动初期会出现产气不稳定现象,经过2个月的运行之后系统达到稳定状态。在有机负荷达到2.73 kg COD/(m3·d)时,各级罐体仍能稳定运行,总产气的45%集中在1号罐。在系统启动初期,螺旋霉素不能被明显降解。运行约80 d后,整个体系达到了快速降解螺旋霉素的状态,在2.73 kg COD/(m3·d)的有机负荷率下,螺旋霉素降解率达到97%,同时可溶性COD降解率也达到了90%。

关 键 词:多级厌氧反应器系统  螺旋霉素  化学需氧量  菌渣  降解

Performance of four stages anaerobic reactor system in treatment of spiramycin manufacturing biowaste
Zhu Pei,Zhang Jianbin,Li Jian,Shao Lei,Chu Ju and Chen Daijie.Performance of four stages anaerobic reactor system in treatment of spiramycin manufacturing biowaste[J].Techniques and Equipment for Environmental Pollution Control,2014,8(2):703-708.
Authors:Zhu Pei  Zhang Jianbin  Li Jian  Shao Lei  Chu Ju and Chen Daijie
Institution:1. State Key Laboratory of Bioreactor Engineering, East China University of Science & Technology, Shanghai 200237, China;2. State Key Laboratory of New Drug & Pharmaceutical Process, Shanghai Institute of Pharmaceutical Industry, Shanghai 200040, China;2. State Key Laboratory of New Drug & Pharmaceutical Process, Shanghai Institute of Pharmaceutical Industry, Shanghai 200040, China;2. State Key Laboratory of New Drug & Pharmaceutical Process, Shanghai Institute of Pharmaceutical Industry, Shanghai 200040, China;2. State Key Laboratory of New Drug & Pharmaceutical Process, Shanghai Institute of Pharmaceutical Industry, Shanghai 200040, China;1. State Key Laboratory of Bioreactor Engineering, East China University of Science & Technology, Shanghai 200237, China;3. China State Institute of Pharmaceutical Industry, Shanghai 200040, China
Abstract:Spiramycin manufacturing biowaste was treated by a four stages anaerobic reactor system. The volume of the system was 44 L being divided into four 11 L stages, each of the stage was connected by series. The system was operated with three steps in the organic loading rate (OLR) of 1.27, 1.82 and 2.73 kg COD/(m3·d). The process performance of the system was characterised in terms of its biogas volume and spiramycin reduction. The system could reach its stable state in biogas production after two month operation. About 45 percent of all biogas was produced from the stage 1 at the OLR of 2.78 kg COD/(m3·d). Though spiramycin was not eliminated rapidly at the beginning, after 80 days, an average of 97% spiramycin and 90% COD reduction were achieved at the OLR of 2.78 kg COD/(m3·d), indicating that this antibiotic could be degraded efficiently in the anaerobic reactor system.
Keywords:four stages anaerobic reactor system  spiramycin  COD  manufacturing biowaste  degradation
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