| 碘代X射线造影剂的环境浓度、分析方法与毒性评估研究进展 |
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| 引用本文： | 杨鹤云,李晓良,王子,陈磊,孔赟,郑兴.碘代X射线造影剂的环境浓度、分析方法与毒性评估研究进展[J].环境化学,2021,40(1):141-149. |
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| 作者姓名： | 杨鹤云 李晓良 王子 陈磊 孔赟 郑兴 |
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| 作者单位： | 西安理工大学西北旱区生态水利国家重点实验室,西安,710048;国家环保设备质量监督检验中心(江苏),宜兴,214205 |
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| 基金项目： | 国家自然科学基金(51878555);江苏省自然科学基金青年基金(BK20150165)资助。 |
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| 摘 要： | 碘代X射线造影剂(ICMs)是使用最广泛的血管内药物,近年来在水生环境中频繁检出.由于其高稳定性、高极性和持久性,ICMs会在水生环境中持续存在并且难以被降解.在水生环境中会与消毒剂、天然有机物结合生成具有毒性的消毒副产物(DBPs),由于其本身毒性以及转化产物DBPs的毒性增强了环境健康风险,进而引发了人们的密切关注.本文介绍了ICMs的环境浓度、分析方法以及毒性风险.重点描述了ICMs的前处理技术、检测方法及ICMs毒性评价现状,并展望了以后ICMs毒性的研究方向.
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| 关 键 词： | 碘代X射线造影剂 环境浓度 分析方法 毒性评估 消毒副产物 |
Research progress on the environment concentration,analytical methods and toxicity evaluation of iodinated X-ray contrast medias |
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| YANG Heyun,LI Xiaoliang,WANG Zi,CHEN Lei,KONG Yun,ZHENG Xing.Research progress on the environment concentration,analytical methods and toxicity evaluation of iodinated X-ray contrast medias[J].Environmental Chemistry,2021,40(1):141-149. |
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| Authors: | YANG Heyun LI Xiaoliang WANG Zi CHEN Lei KONG Yun ZHENG Xing |
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| Institution: | (State Key Laboratory of Eco-hydraulics in Northwest Arid Region,Xi'an University of Technology,Xi'an,710048,China;National Environmental Protection Equipment Quality Supervision and Inspection Center(Jiangsu),Yixing,214205,China) |
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| Abstract: | Iodinated X-ray contrast medias(ICMs) are the most widely used intravascular agents and have been frequently detected in aquatic environments in recent years. Due to its high stability, high polarity and persistence, ICMs will persist in aquatic environments and be difficult to degrade. In the aquatic environment, it will combine with disinfectants and natural organic substances to form toxic disinfection by-products(DBPs). Due to its own toxicity and the toxicity of the transformed product DBPs, it has aroused people′s close attention. The environmental concentration, analysis method and toxicity risk of ICMs were introduced. This paper mainly described the pretreatment technology, detection methods and toxicity evaluation of ICMs, and prospected the future research direction of ICMs toxicity. |
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| Keywords: | iodinated X-ray contrast medias environmental concentration analytical method toxicity evaluation disinfection by-product |
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