Synthesis of anti-12-hydroxyendrin and 12-ketoendrin,the two major mammalian metabolites of endrin |
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Authors: | C.T. Bedford R.K. Harrod |
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Affiliation: | Shell Research Limited, Tunstall Laboratory, Sittingbourne, Kent. UK |
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Abstract: | The first synthesis of and 12-hydroxylated derivatives of endrin (and thence 12-ketoendrin) has been accomplished in three steps starting from hexachlorocyclopentadiene and 7-benzoyloxy [2.2.1]hepta-2,5-diene. |
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