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气密性高等级生物安全实验室的负压控制
引用本文:张宗兴,李艳菊,祁建城,张金明,赵歆治,刘俊杰.气密性高等级生物安全实验室的负压控制[J].中国安全科学学报,2010,20(6).
作者姓名:张宗兴  李艳菊  祁建城  张金明  赵歆治  刘俊杰
作者单位:1. 军事医学科学院卫生装备研究所,国家生物防护装备工程技术研究中心,天津,300161
2. College of Engineering,University of Nebraska-Lincoln.Lincoln,Nebraska,USA
3. 天津大学环境科学与工程学院,天津,300072
基金项目:"十一五"国家科技支撑计划项目 
摘    要:提出漏风量换气次数的概念,并以此作为评价气流控制阀是否适用于生物安全实验室压差控制的指标;提出引入附加漏风量的气密性生物安全实验室压差控制策略。进行对比实验,研究实验室在无人为漏风量与引入人为漏风量这两种情况下启动、微扰动、关门等工况下实验室的压差波动情况,其结果显示在引入人为漏风量情况下实验间压差波动范围减小、稳定速度加快。从而说明引入附加漏风量的压差控制策略在气密性生物安全实验室的压差控制方面具有重要的实际应用价值。

关 键 词:生物安全实验室  围护结构  气密  压差控制  负压

Negative Pressure Difference Control in Airtight High-level Bio-safety Laboratory
ZHANG Zong-xing,LI Yan-ju,QI Jian-cheng,ZHANG Jin-ming,ZHAO Qin-zhi,LIU Jun-jie.Negative Pressure Difference Control in Airtight High-level Bio-safety Laboratory[J].China Safety Science Journal,2010,20(6).
Authors:ZHANG Zong-xing  LI Yan-ju  QI Jian-cheng  ZHANG Jin-ming  ZHAO Qin-zhi  LIU Jun-jie
Abstract:A new concept of air leakage change rate was put forward,which could be used as the guideline for estimating whether the air volume valve could be applicable to the negative pressure difference control in bio-safety laboratory;and a strategy of introducing man-made air leakage for pressure difference control in airtight bio-safety laboratory was proposed.Comparison experiments were conducted to test the pressure fluctuation at the state of laboratory startup,small disturbance,door closing in the laboratory on natural air leakage condition and introduced man-made air leakage condition respectively,and the results indicate that the fluctuating range of pressure difference becomes small and goes to stable more rapidly on introduced man-made air leakage condition.It shows that the method of introducing man-made air leakage for pressure difference control is applicable to airtight bio-safety laboratory.
Keywords:bio-safety laboratory  containment enclosure  airtight  pressure difference control  negative pressure
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