| Metabolism of benzo[a]pyrene in peroxynitrite/Fe(III) porphyrin system |
| |
| 作者姓名： | LUO Yun-jing LIN Tai-feng ZHANG Shu-fen LIU Rui ZHONG Ru-gang |
| |
| 作者单位： | LUO Yun-jing，LIN Tai-feng，ZHANG Shu-fen，LIU Rui，ZHONG Ru-gang College of Life Science and Bioengineering，Beijing University of Technology，Beijing 100022，China. |
| |
| 基金项目： | Project supported by the Beijing Natural Science Foundation (No. 2052004)，the Beijing Nova Programme (No. 2003B05)，the National Natural Science Foundation of China (No. 20605002). |
| |
| 摘 要： | The peroxynitrite/porphyrin biomimetic system was established to investigate the effects of peroxynitrite on benzoa]pyrene (Ba]P) metabolism. Three model systems consisting of different iron porphyrins were compared, and the results showed that the peroxynitrite/T(p-Cl)PPFeCl system was the highest catalytic efficiency in the metabolism of Ba]P. We analyzed the Ba]P metabolites produced from this system by RP-HPLC method and firstly identified the formation of nitrobenzoa]pyrenes which are the special metabolites of Ba]P induced by peroxynitrite.
|
| 收稿时间： | 2006/11/8 0:00:00 |
| 修稿时间： | 2007/1/15 0:00:00 |
Metabolism of benzo[a]pyrene in peroxynitrite/Fe(III) porphyrin system |
| |
| LUO Yun-jing,LIN Tai-feng,ZHANG Shu-fen,LIU Rui,ZHONG Ru-gang.Metabolism of benzo[a]pyrene in peroxynitrite/Fe(III) porphyrin system[J].Journal of Environmental Sciences,2007,19(4):385-386. |
| |
| Authors: | LUO Yun-jing LIN Tai-feng ZHANG Shu-fen LIU Rui and ZHONG Ru-gang |
| |
| Institution: | College of Life Science and Bioengineering, Beijing University of Technology, Beijing 100022, China. E-mail: luoyj@bjut.edu.cn,College of Life Science and Bioengineering, Beijing University of Technology, Beijing 100023, China.,College of Life Science and Bioengineering, Beijing University of Technology, Beijing 100024, China.,College of Life Science and Bioengineering, Beijing University of Technology, Beijing 100025, China. and College of Life Science and Bioengineering, Beijing University of Technology, Beijing 100026, China. |
| |
| Abstract: | The peroxynitrite/porphyrin biomimetic system was established to investigate the effects of peroxynitrite on benzoa]pyrene (Ba]P) metabolism. Three model systems consisting of different iron porphyrins were compared, and the results showed that the peroxynitrite/T(p-Cl)PPFeCl system was the highest catalytic efficiency in the metabolism of Ba]P. We analyzed the Ba]P metabolites produced from this system by RP-HPLC method and firstly identified the formation of nitrobenzoa]pyrenes which are the special metabolites of Ba]P induced by peroxynitrite. |
| |
| Keywords: | peroxynitrite benzo[a]pyrene metabolism nitrobenzo[a]pyrenes |
| 本文献已被 CNKI 等数据库收录！ |
| 点击此处可从《环境科学学报(英文版)》浏览原始摘要信息 |
| 点击此处可从《环境科学学报(英文版)》下载免费的PDF全文 |
