| 基于人体健康风险的水污染事件遗传性致癌物安全浓度研究 |
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| 引用本文： | 罗锦洪,郑丙辉,付青,黄民生. 基于人体健康风险的水污染事件遗传性致癌物安全浓度研究[J]. 环境科学, 2012, 33(2): 342-345 |
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| 作者姓名： | 罗锦洪 郑丙辉 付青 黄民生 |
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| 作者单位： | 华东师范大学资源与环境科学学院,上海 200062; 中国环境科学研究院环境基准与风险评估国家重点实验室,北京100012;中国环境科学研究院环境基准与风险评估国家重点实验室,北京100012;中国环境科学研究院环境基准与风险评估国家重点实验室,北京100012;华东师范大学资源与环境科学学院,上海 200062 |
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| 基金项目： | 国家水体污染控制与治理科技重大专项(2009ZX07528-003,2009ZX07419-003) |
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| 摘 要： | 确定水污染事件中遗传性致癌物短期暴露安全浓度,是目前我国水环境管理中急需解决的问题.在假设遗传性致癌物暴露剂量与致癌风险呈线性相关的前提下,提出了水体中遗传性致癌物安全浓度计算流程,建立了采用遗传性致癌物终生暴露安全浓度计算短期暴露安全浓度的方法.在我国2000～2010年间发生的60起水污染事故中,特征污染物为砷的水污染事件为6起,占总污染事件比例为10%,这一结果表明砷为我国水污染事件中高发的特征污染物.根据水污染事件遗传性致癌物短期暴露安全浓度计算方法,得出砷短期暴露安全浓度为0.5 mg.L-1,表明该方法在水污染事件应急管理中具有一定的可行性.
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| 关 键 词： | 水污染事件 遗传性致癌物 短期暴露 人体健康风险 安全浓度 砷 |
| 修稿时间： | 2011-06-23 |
Safety Concentration of Genotoxic Carcinogens in Water Pollution Accident Based on Human Health Risk |
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| LUO Jin-hong,ZHENG Bing-hui,FU Qing and HUNG Min-sheng. Safety Concentration of Genotoxic Carcinogens in Water Pollution Accident Based on Human Health Risk[J]. Chinese Journal of Environmental Science, 2012, 33(2): 342-345 |
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| Authors: | LUO Jin-hong ZHENG Bing-hui FU Qing HUNG Min-sheng |
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| Affiliation: | School of Resource and Environmental Sciences, East China Normal University, Shanghai 200062, China; State Key Laboratory of Environmental Criteria and Risk Assessment, Chinese Research Academy of Environmental Sciences, Beijing 100012, China;State Key Laboratory of Environmental Criteria and Risk Assessment, Chinese Research Academy of Environmental Sciences, Beijing 100012, China;State Key Laboratory of Environmental Criteria and Risk Assessment, Chinese Research Academy of Environmental Sciences, Beijing 100012, China;School of Resource and Environmental Sciences, East China Normal University, Shanghai 200062, China |
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| Abstract: | It was an urgent problem to determine short-term exposure safety concentration of genetic carcinogens in water pollution accident in China. Based on the hypothesis that the relationship between exposure dosage and carcinogenic risk was linear, the calculation process of genetic carcinogens safety concentration was put forwarded, and the method using life-time exposed safety concentration to calculate short-term exposure safety concentration was set up. Based on the statistical result of water pollution accident occurred in china during 2000-2010, arsenic was a major characteristic contaminate in water pollution accident. According to the method of short-term exposure safety concentration of genotoxic carcinogens, the safety concentration of arsenic was 0.5 mg·L-1, it showed that the method was feasible in emergence management of water pollution accident. |
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| Keywords: | water pollution accident genotoxic carcinogens short-term exposure human health risk assessment safety concentration arsenic |
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