Effect-related monitoring: estrogen-like substances in groundwater |
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Authors: | Bertram Kuch Frieder Kern Jörg W Metzger Karl Theo von der Trenck |
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Institution: | 1.Institut für Siedlungswasserbau, Wassergüte- und Abfallwirtschaft,Stuttgart,Germany;2.Landesanstalt für Umwelt, Messungen und Naturschutz Baden-Württemberg (LUBW),Karlsruhe,Germany |
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Abstract: | Background, aim, and scope Concentration monitoring as a basis for risk assessment is a valid approach only if there is an unambiguous relation between
concentration and effect. In many cases, no such unambiguous relation exists, since various substances can exert the same
effect with differing potencies. If some or all of these substances contributing to a biological effect are unknown, effect-related
monitoring becomes indispensable. Endocrine-disrupting substances in water bodies, including the groundwater, are a prominent
example of such a case. The aim of the investigations described here was to detect hormonally active substances in the groundwater
downstream of obsolete landfills by using the E-screen assay and to possibly assign the biological effect to individual chemical
compounds by means of instrumental analyses carried out in parallel. |
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