| 低浓度下4个取代苯污染物与硝酸铅的混合对发光菌的联合毒性 |
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| 引用本文： | 黄伟英,陈鸿汉,刘菲.低浓度下4个取代苯污染物与硝酸铅的混合对发光菌的联合毒性[J].生态环境,2010(1):57-62. |
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| 作者姓名： | 黄伟英 陈鸿汉 刘菲 |
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| 作者单位： | 中国地质大学(北京)水资源与环境工程北京市重点实验室; |
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| 基金项目： | 国家水体污染控制与治理科技重大专项课题项目(2009ZX07212-003); 国家自然科学基金项目(40972162) |
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| 摘 要： | 多种污染物混合特别是低浓度下的混合对生物的联合毒性是生态毒理学研究的热点之一。选择了3类污染物苯酚、间甲基苯酚、苯胺、对硝基苯胺、硝酸铅，采用美国微板光度计测定了它们对发光菌青海弧菌．Q67（Vibrio-qinghaiensissp-Q67）的单一及联合毒性。应用非线性拟合技术模拟了这5种物质及其混合物的剂量．效应曲线，硝酸铅可用Logit模型模拟，其它4个物质能用Weibull模型准确描述，所有拟合相关系数在0．98以上，均方根误差在O．02以下。根据纯物质的EC50值，获得这5个物质的毒性强弱顺序：硝酸铅〉对硝基苯胺〉间甲基苯酚〉苯酚〉苯胺。混合实验设计了各物质在EC50、EC1、无观察效应浓度（noobserved effectcon centration，NOEC）比例的混合。用浓度加和（doseaddition，DA）和独立作用模型（independentaction，IA）对混合物毒性进行预测。IA基本准确预测了这5个物质在各自EC50混合的毒性。DA与队模型都稍微过高地预测了以EC。及NOEC浓度比例混合的联合毒性，但都在毒理学实验容许的范围之内。这5个物质以NOEC混合时对测试生物Q67没有产生明显毒性，但是还不能判定这些物质在此浓度下混合是安全的。污染物在各自的NOEC浓度下混合是否对其它生物有潜在的威胁还需更多毒理学实验支持。
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| 关 键 词： | 苯酚 苯胺 硝酸铅 无观察效应浓度（NOEC） 青海弧菌 毒性 |
Combined toxicity of four substituted benzene pollutants and lead nitrate at low concentrations on photobacteria |
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| HUANG Weiying,CHEN Honghan,LIU Fei China University of Geosciences //Beijing Key Laboratory of Water Resources & Environmental Engineering,Beijing ,China.Combined toxicity of four substituted benzene pollutants and lead nitrate at low concentrations on photobacteria[J].Ecology and Environmnet,2010(1):57-62. |
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| Authors: | HUANG Weiying CHEN Honghan LIU Fei China University of Geosciences //Beijing Key Laboratory of Water Resources & Environmental Engineering Beijing China |
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| Institution: | HUANG Weiying,CHEN Honghan,LIU Fei China University of Geosciences (Beijing)//Beijing Key Laboratory of Water Resources & Environmental Engineering,Beijing 100083,China |
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| Abstract: | Combined toxicity of multi-component mixture (especially at low concentrations) to biology is a hot issue in the field of ecotoxicology.The toxicity of each component and the combined toxicity of mixtures on Vibrio-qinghaiensis sp.-Q67 were determined by micro-plate Luminometre in this study.The components investigated included phenols (phenol and 3-methyl-phenol),anilines (aniline and p-nitroaniline),and lead nitrate.The Dose-Response curves of these substances were obtained by non-linear fitting.The exper... |
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| Keywords: | phenol aniline lead nitrate no observed effect concentration (NOEC) Vibrio-qinghaiensis sp -Q67 toxicity |
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