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真菌深黄被孢霉及其提取物对高脂血症的作用
引用本文:蔡双莲,李敏,吴雪伟.真菌深黄被孢霉及其提取物对高脂血症的作用[J].应用与环境生物学报,2004,10(3):375-377.
作者姓名:蔡双莲  李敏  吴雪伟
作者单位:福建师范大学生物工程学院,福州,350007
摘    要:探讨深黄被孢霉菌粉及其提取物对实验性高脂血症小鼠血脂的影响 .用高脂饲料造成昆明小白鼠高脂血症动物模型 ,以力平之为阳性对照 ,测定深黄被孢霉及其提取物灌胃小鼠 6 0d后 ,对高脂血症小鼠的血清总胆固醇(TC)、甘油三酯 (TG)、高密度脂蛋白 (HDL)含量的影响 .结果表明 :深黄被孢霉及其提取物可使小鼠血清TG、TC降低(P <0 .0 5或P <0 .0 1) ,并能显著提高血清中HDL水平 (P <0 .0 1) ,且脂溶性提取物和水溶性提取物之间对TG、TC的降低具有协同效果 .图 1表 1参 6

关 键 词:真菌深黄被孢霉  脂溶性成分  水溶性成分  高脂血症
修稿时间:2003年7月2日

THERAPEUTIC EFFECT OF MORTIERELLA ISABELLINA EXTRACTS ON HYPERLIPIDEMIA
CAI Shuanglian,LI Min $$$$ WU Xuewei.THERAPEUTIC EFFECT OF MORTIERELLA ISABELLINA EXTRACTS ON HYPERLIPIDEMIA[J].Chinese Journal of Applied and Environmental Biology,2004,10(3):375-377.
Authors:CAI Shuanglian  LI Min $$$$ WU Xuewei
Abstract:The effects of Mortierella isabellina power and its extracts on reducing blood lipid were investigated. Experimental mice of Kunming strain with hyperlipidemia were fed with M. isabellina power and the extracts for two months, and then the levels of serum total cholesterol (TC), triglyceride (TG) and high density lipoprotein (HDL) were tested. The results showed that M. isabellina and its extracts had very strong positive effects on prevention and regulation of hyperlipidemia in rats: the serum TC and the TG in rats' serum were lower, and the HDL in rats' serum were higher in the animals of experimental group than in those of control. Fig 1, Tab 1, Ref 6
Keywords:Mortierella isabellina  lipid  soluble extract  water  soluble extract  hyperlipidemia
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