Effects of aerobic exercise on histopathology and toxicology of ZnO and nano ZnO in male rats |
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| Authors: | Parvin Farzanegi Hajar Abbaszadeh Asieh Abbassi Daloii Mozhgan Kazemi Masoumeh Sabbaghian Afsaneh Shoeibi |
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| Institution: | 1. Department of Exercise Physiology, Sari Branch, Islamic Azad University, Sari, Iran;2. Exercise Physiology Department, Ayatollah Amoli Branch, Islamic Azad University, Amol, Iran |
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| Abstract: | The effects of four weeks of aerobic exercise on histopathological and toxicological effects induced by nano ZnO and ZnO powders in male rats were evaluated. Tissue sections of liver and kidneys of ZnO and nano ZnO rats showed some histopathological changes, which were partly reverted by exercise. ZnO and nano ZnO treatments caused an increase in the level of tumor necrosis factor-α, while the mean of Interleukin 10 was declined. Exercise training enhanced the mean value of and declined mean level of in rats treated with ZnO and nano ZnO. The ZnO and ZnO groups demonstrated the highest means of insulin resistance, low density lipoprotein, cholesterol, triglyceride levels and lower mean value of compared to the other groups, while exercise resulted in improvement in mean of these factors. |
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| Keywords: | ZnO nano ZnO aerobic exercise liver and kidney function inflammation |
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