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Prenatal paternity testing by dna analysis |
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| Authors: | A Lobbiani A Nocco P Vedrietti B Brambati G Colucci MD |
| Institution: | 1. Molecular Biology Laboratory, Clonit SpA, Milan, Italy
Laboratorio TOMA, Busto Arsizio, Italy;2. Fondazione Centra Studi di Patologia Molecolare Applicata alia Clinica, Milan, Italy;3. Centre for Reproductive Medicine, Milan, Italy |
| Abstract: | Prenatal paternity testing was evaluated by DNA analysis in chorionic villus biopsies obtained during the 7th-22nd weeks of gestation. Using highly polymorphic variable number of tandem repeats (VNTR) probes, we analysed four cases consisting of mother/child/alleged father trios. In all cases, we were able to detect maternal and paternal alleles and could establish or exclude paternity. The application of DNA analysis represents a new important diagnostic aid for all cases that require a prenatal identification of paternity. |
| Keywords: | Paternity testing Prenatal diagnosis DNA analysis |