Prenatal diagnosis of twin zygosity by DNA ‘fingerprint’ analysis |
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| Authors: | Z Appelman M Manor N Magal B Caspi M Shohat I Blickstein |
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| Institution: | 1. Department of Obstetrics and Gynecology, Kaplan Hospital, Rehovot 76100, Israel;2. Genetic Unit, Beilinson Medical Center, Petah Tikvah, Israel |
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| Abstract: | A twin pregnancy with one hydrocephalic fetus with oligohydramnios is presented. Sonographic evaluation could not exclude monochorionicity. Before considering selective feticide, blood samples from both fetuses were examined for DNA ‘fingerprint’ analysis. The different banding patterns of the blood samples established dizygosity. This procedure is suggested in cases where sonography fails to determine chorionicity. |
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| Keywords: | Twins zygosity prenatal diagnosis DNA ‘fingerprinting’ |
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