Evaluation of the toxicity of tetrabromobisphenol A and some of its oxidation products using a micro-scale algal growth inhibition test |
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| Authors: | Kazuto Sazawa Yoshiki Furuhashi Noriko Hata Shigeru Taguchi Masami Fukushima |
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| Institution: | 1. Department of Environmental Biology and Chemistry, Graduate School of Science and Engineering for Research, University of Toyama, Toyama, Japan;2. Laboratory of Chemical Resources, Division of Sustainable Resources Engineering, Graduate School of Engineering, Hokkaido University, Sapporo, Japan |
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| Abstract: | A micro-scale algal growth inhibition (μ-AGI) test using a common micro-plate based fluorometric detection was used to demonstrate the effects of humic substances (HSs) on the toxicity of tetrabromobisphenol A (TBBPA) and its oxidative decomposition products 2,5-dibromo-1,4-benzoquinone (2,5-DBBQ), 2,5-dibromohydroquinone (2,5-DBHQ), 2,6-dibromobenzoquinone (2,6-DBBQ), and 2,6-dibromophenol (2,6-DBP) to Pseudokirchneriella subcapitata. The EC50 values were: EC50(TBBPA) = 7 mg L?1, EC50(2,5-DBHQ) = 7 mg L?1, EC50(2,5-DBBQ) = 19 mg L?1, EC50(2,6-DBP) = 49 mg L?1, and EC50(2,6-DBBQ) = 13 mg L?1. The toxicity of the chemicals was slightly lower in the presence of HA. The toxicity of TBBPA decomposed by a biomimetic catalytic system consisting of iron (III) 5,10,15,20-tetrakis (p-sulfonatophenyl) porphyrin (Fe(III)-TPPS) and KHSO5 was also evaluated using P. subcapitata and Chlamydomonas reinhardtii. |
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| Keywords: | algal growth inhibition test tetrabromobisphenol A Pseudokirchneriella subcapitata humic acid |
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