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Potential correlation between perfluorinated acids and liver morphology in East Greenland polar bears (Ursus maritimus)
Authors:Christian Sonne PhD  DVM  VMD  MVSc  Rossana Bossi  Rune Dietz  Pall S Leifsson  Frank F Rigét  Erik W Born
Institution:1. Section for Contaminants, Effects and Marine Mammals, Department of Arctic Environment , National Environmental Research Institute , University of Aarhus, Frederiksborgvej 399, PO Box 358, DK-4000 Roskilde, Denmark csh@dmu.dk;3. Department of Atmospheric Environment , National Environmental Research Institute , Frederiksborgvej 399, University of Aarhus, PO Box 358, DK-4000 Roskilde, Denmark;4. Section for Contaminants, Effects and Marine Mammals, Department of Arctic Environment , National Environmental Research Institute , University of Aarhus, Frederiksborgvej 399, PO Box 358, DK-4000 Roskilde, Denmark;5. Faculty of Life Sciences, Department of Veterinary Pathobiology , University of Copenhagen , Bülowsvej 17, DK-1870 Frederiksberg, Denmark;6. Greenland Institute of Natural Resources , PO Box 570, DK-3900 Nuuk, Greenland
Abstract:In this study, residual concentrations of chlorpyrifos (CPF) were determined in feed (40) and fodder (25) samples collected from various locations of Tarai region of Uttarakhand. For extracting residues, liquid–liquid partition followed by alumina column clean up was used and the detection and quantification of residues was undertaken with the help of high-performance liquid chromatography using C18 column and diode array detector at 220?nm. Of the total 40 feed samples analyzed, 7 (17.5%) samples were found positive for CPF with the mean residual concentration of 0.058?µg?g?1; while out of 25 fodder samples, CPF residues were detected in a single (4%) sample with residual concentration of 0.39?µg?g?1. However, none of the feed or fodder samples contained CPF residues above the prescribed limit.
Keywords:East Greenland  histopathology  liver  perfluorohexanesulfonate  perfluorooctanesulfonamide  perfluorooctanesulfonate  perfluorooctanoic acid  PFAs  PFHS  PFOA  PFOS  PFOSA  polar bear  Ursus maritimus
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