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Abnormal Shh and FOXC2 expression correlates with aberrant lymphatic development in human fetuses with increased nuchal translucency
Authors:Yolanda M. de Mooij  Nynke M. S. van den Akker  Mireille N. Bekker  Margot M. Bartelings  Lambertus J. Wisse  John M. G. van Vugt  Adriana C. Gittenberger-de Groot
Affiliation:1. Department of Anatomy and Embryology, Leiden University Medical Center, Leiden, The Netherlands

Department of Obstetrics and Gynecology, VU University Medical Center, Amsterdam, The Netherlands;2. Department of Anatomy and Embryology, Leiden University Medical Center, Leiden, The Netherlands

Department of Cardiology, Cardiovascular Research Institute Maastricht, Maastricht University, Maastricht, The Netherlands;3. Department of Obstetrics and Gynecology, VU University Medical Center, Amsterdam, The Netherlands;4. Department of Anatomy and Embryology, Leiden University Medical Center, Leiden, The Netherlands

Abstract:
Keywords:nuchal translucency  lymphatic development  Shh  FOXC2  jugular lymphatic sac
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