肼与苯肼对斑马鱼胚胎和仔鱼的毒性研究

采用国际新推出的鱼类长效应测定技术对水中肼与苯肼的毒性进行了测定。结果表明,胼对鱼类具有很大毒性,对斑马鱼胚胎发育有影响,最低影响浓度(LOEC)为0.049mg/L,无影响浓度(NOEC)为0.0245mg/L,对仔鱼存活的最低影响浓度为0.0035mg/L,无影响浓度为0.00175mg/L。苯肼的毒性比肼大,对斑马鱼鱼卵孵化的LOEC为0.0078mg/L,NOEC为0.0039mg/L,对仔鱼生存的LOEC为0.00098mg/L,NOEC为0.00049mg/L.结果表明,仔鱼比鱼卵对肼及苯肼的毒性更敏感.笔者认为斑马鱼胚胎和仔鱼毒性实验方法是一个能反映毒物对鱼类长期毒性效应的快速实验技术值得推广使用。

Toxicity of Hydrazine and Phenylhydrazin to Embryos and Larvae of Zebrafish (Brachysanio rerio)

The Toxicities of Hydrazine and phenylhydrazin to embryos and larvae of zebrafish, Brachydanio rerio, were studied under standardized conditions. Expo- sures to the chemicals started at the blastula stage and the effect on hatching and survival were monitored for 15 days. The results showed thai toxicities of phenylhydrazin to both embryos and larvae were more than those of hydrazine. The LOEC (Lowest Observed Effect Concentration) for hatching was 0.049 mg/L for hydrazine and 0.0078mg/L for phenylhydrazin, the LOEC for survival of larvae was 0.0035mg/L for hydrazine and 0.00098tng/L for phenvlhydrazin, respectively. The NOEC (No Observed Effect Concentration) for hatching was 0.0245rng/L for hydrazine and 0.0039mg/L for phenylhydrazin and the NOEC for survival of larvae was 0.00175mg 'L for hydrazine and 0.00049 mg/L for phenylhydrazin, respectively. The safe concentration was 0.00175mg/L for hydrazine and 0.00049mg/L for pheylhdrazin.