Determination of mutagenic potential and organic contaminants of Great Lakes drinking water |
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| Authors: | David T. Williams Earle R. Nestmann Guy L. LeBel Frank M. Benoit Rein Otson E.G.H. Lee |
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| Affiliation: | Bureau of Chemical Hazards Environmental Health Directorate, Department of National Health and Welfare, Ottawa, Ontario Canada K1A OL2;B.C. Research, Vancouver, British Columbia, Canada V6S 2L2 |
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| Abstract: | ![]()
Extracts of organic compounds were obtained, using XAD-2 macroreticular resin, from drinking water supplies in 12 Great Lakes municipalities. The extracts were tested for mutagenic potential using the Salmonella/mammalian-microsome assay and analysed for organochlorine pesticides, polyaromatic hydrocarbons, organophosphorous pesticides and trialkyl-arylphosphates. Grab samples of drinking water were also analysed for volatile organic compounds. Dose-related increases in mutagenicity were found in extracts from 11 of the drinking water supplies. |
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