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Genotoxicity study of high aspect ratio silver nanowires |
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| Authors: | Mohammad Charehsaz Sahin Coskun Husnu Emrah Unalan Rengin Reis Sinem Helvacioglu Ashok Kumar Giri |
| Affiliation: | 1. Department of Toxicology, Faculty of Pharmacy, Yeditepe University, Istanbul, Turkey;2. Department of Metallurgical and Materials Engineering, Middle East Technical University, Ankara, Turkey;3. Molecular Genetics Division, CSIR-Indian Institute of Chemical Biology, Kolkata, India |
| Abstract: | The genotoxicity potential of silver nanowires synthesized via the solution-based polyol method has been investigated. They were found to be non-mutagenic in three Salmonella strains and were not genotoxic in a clastogenicity assay in mice. Residual surfactant was found to have an effect on the toxicological properties of the nanowires by increasing the rate of Ag+ release. Residual surfactant can be easily degraded via a UV treatment. |
| Keywords: | Silver nanowires mutagenicity in vivo chromosomal aberration test Ames test |