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Synthesis and anti-microbial activity of hydroxylammonium ionic liquids |
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| Authors: | Ismail Hossain M El-Harbawi Mohanad Noaman Yousr Abdulhadi Bustam Mohd Azmi B Alitheen Noorjahan Banu Mohamed Affandi Nor Azrin Hefter Glenn Yin Chun-Yang |
| Institution: | a Chemical Engineering Department, Universiti Teknologi PETRONAS, 31750, Bandar Seri Iskandar, Tronoh, Perak, Malaysia b Department of Cell and Molecular Biology, Faculty of Biotechnology and Biomolecular Sciences, Universiti Putra Malaysia, 43400, Serdang, Selangor, Malaysia c School of Chemical and Mathematical Sciences, Murdoch University, Murdoch, 6150 WA, Australia |
| Abstract: | Eight hydroxylammonium-based room temperature ionic liquids (ILs) have been synthesized by acid-base neutralization of ethanolamines with organic acids. The ILs were characterized by infrared and nuclear magnetic resonance spectroscopies and elemental analysis. Their anti-microbial activities were determined using the well-diffusion method. All eight ILs were toxic to Staphylococcus aureus, while 2-hydroxyethylammonium lactate and 2-hydroxy-N-(2-hydroxyethyl)-N-methylethanaminium acetate showed high anti-microbial activity against a wide range of human pathogens. |
| Keywords: | Hydroxyl ammonium ionic liquids Anti-microbial screening Inhibition potential Human pathogens |
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