| Chemical constituents of one endophytic fungus isolated from Cordyceps sinensis北大核心CSCD |
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| 作者单位： | 1.Key Laboratory of Standardization of Chinese Herbal Medicine, Ministry of Education, State Key Laboratory Breeding of Systematic Research Development and Utilization, Chinese Medical Resources, Sichuan Province and MOST, Pharmacy Department, Chengdu Univer611137; |
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| 基金项目： | Young Teachers’ Innovation Fundation of Chengdu University of Traditional Chinese Medcine；Education Department of Sichuan Province；Sichuan Province Youth Science and Technology Innovation Team |
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| 摘 要： | The study focused on the analysis of the chemical constituents of ethyl acetate extracts of Penicillium herquei, an endophyte of Cordyceps sinensis. The compounds were isolated and purified by chromatographic procedures and identified on the basis of spectral methods. Eleven compounds were identified: 2′,4′-dihydroxy-3′,5′-dimethylacetophenone (1), vanillin (2), 3-oxo-α-ionone (3), 3,3,5-trimethyl-4-(3-oxo-1-butenyl)cyclohexan-1-one (4), p-hydroxybenzaldehyde (5), p-hydroxyacetophenone (6), methyl p-hydroxyphenylacetate (7), cyclo-(Pro-Ile) (8), cyclo-(Pro-Val) (9), 4-methoxyphenylacetic acid (10), and cyclo-(4-methyl-Pro-Val) (11). Benzaldehydes, ionones, and cyclodipeptides are the major metabolites of the P. herquei from C. sinensis. © 2018 Science Press. All rights reserved.
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