Insecticides biomarker responses on a freshwater fish Corydoras paleatus (Pisces: Callichthyidae) |
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| Authors: | Izonete Cristina Guiloski Stéfani Cibele Rossi Cesar Aparecido da Silva Helena Cristina Silva de Assis |
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| Institution: | 1. Pharmacology Department , Federal University of Paraná , Curitiba-PR , Brazil;2. Ecology and Conservation Post-graduation Program , Federal University of Paraná , Curitiba-PR , Brazil |
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| Abstract: | This study was undertaken to investigate the effects of sublethal concentration of three different classes of insecticides (carbamate, organophosphate, and pyrethroid compounds) on the freshwater fish Corydoras paleatus. For this purpose, fish were exposed for 96 hours to commercial pesticides. Different biomarkers were analyzed as levels of lipid peroxidation (LPO), piscine micronucleus test, and enzymatic activities of catalase (CAT), glutathione S-transferase (GST), and acetylcholinesterase (AChE). The brain AChE was inhibited with carbaryl and methyl parathion, but no inhibition was observed with deltamethrin. The insecticides did not cause oxidative stress or genotoxic effects at the tested concentrations. Further studies are needed to elucidate the biotransformation of Corydoras paleatus insecticides and a possible resistance mechanism. |
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| Keywords: | Bioassay organophosphate carbamate pyrethroid |
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