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醛类化合物-DNA加合物结构研究进展
引用本文:袭著革,戴树桂.醛类化合物-DNA加合物结构研究进展[J].上海环境科学,1999(6).
作者姓名:袭著革  戴树桂
作者单位:南开大学,南开大学 天津 300071,天津 300071
摘    要:综述了环境中常见的7种醛类污染物与DNA形成加合物的结构研究现状,包括单核苷酸-醛试管反应、DBA-醛试管反应、细胞培养、动物体以及人体内所产生的加合物结构的研究方法与结论,并对加合物结构研究的难点和发展方向进行了探讨。

关 键 词:醛类化合物  DNA加合物  结构鉴定

Study Progress on the Structure of DNA Adducts of Aldehyde Compounds
Xi Zhuge Dai Shugui.Study Progress on the Structure of DNA Adducts of Aldehyde Compounds[J].Shanghai Environmental Science,1999(6).
Authors:Xi Zhuge Dai Shugui
Abstract:Study progress of the structure of DNA adducts by 7 kinds of environmental aldehyde pollutants were reviewed, including research methods and conclusion of reaction of aldehydes with deoxynucleosides, DNA cultured cells in vitro, and adducts in rodent and human tissues, the difficulty and future of the structure of DNA adducts were also discussed.
Keywords:Aldehyde compounds DNA adducts Identification of structure
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