Alphafetoprotein,cholinesterases and rapidly adhering cells in the prenatal diagnosis of neural tube defects |
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| Authors: | Mary J Seller Kathleen J Cole Bernadette L Merritt |
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| Institution: | Paediatric Research Unit, The Prince Philip Research Laboratories, Guy's Hospital Medical School, London SEI 9RT, U.K. |
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| Abstract: | Amniotic fluid cholinesterases tested on polyacrylamide gel and rapidly adhering cell analysis were compared in their efficiency at diagnosing fetal neural tube defects in three cases where the alphafetoprotein results were equivocal. While rapidly adhering cells were also equivocal, the cholinesterases consistently gave a clear indication of fetal abnormality. |
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| Keywords: | Prenatal diagnosis Neural tube defects Cholinesterase Alphafetoprotein |
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