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Fibrinopeptide a increases after Chorionic villus sampling
Authors:F Al-Gailani  S Elias  J L Simpson  Dr D Green
Institution:Atherosclerosis Program, Rehabilitation Institute of Chicago, Hematology/Oncology Section, Department of Medicine, and the Section of Human Genetics, Department of Obstetrics and Gynecology Northwestern University Medical School, Chicago, Illinois 60611, U.S.A
Abstract:Fibrinopeptide levels were measured in 20 women during transcervical chorionic villus sampling (CVS). Fibrinopeptide A, a sensitive indicator of fibrinogen cleavage by thrombin, significantly increased in five subjects, whereas there was no change in Bβ peptide, an indicator of fibrinolysis. The data suggest that modest fibrin formation, uncompensated by fibrinolysis, may be induced in some women by CVS.
Keywords:Intravascular coagulation  Chorionic villus sampling  Fibrinopeptide A
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