|
|||||
|
|
Prenatal diagnosis of pericentric inversion of chromosome no. 17 in a twin pregnancy |
|
| Authors: | Gulzar Kassam Andrew T L Chen Marshall F Goldberg Suzanne Trusler Godfrey P Oakley Jr |
| Institution: | 1. Maternal and Infant Care Project, Grady Memorial Hospital and Department of Gynecology & Obsteirics, Emory School of Medicine, Atlanta, Georgia 30322, U.S.A.;2. Birth Defects Branch, Center for Environmental Health, Centers for Disease Control, Public Health Service, U.S. Department of Health and Human Services, Atlanta, Georgia 30333, U.S.A.;3. Genetics Laboratory, Center for Environmental Health, Centers for Disease Control. 1600 Clifton Road, Atlanta, Georgia 30333. U.S.A. |
| Abstract: | Although prenatal genetic diagnosis can usually provide prospective parents with information as to whether their fetus is affected with certain genetic conditions, the presence of twins and the uncertainty about the phenotype of some chromosome variations pose a major dilemma and make genetic counselling very difficult. Here, a case report of an unusual chromosome aberration (pericentric inversion of chromosome no. 17) in a twin pregnancy which was originally suspected to be monoamniotic but later proved to have two sacs was presented. |
| Keywords: | Prenatal diagnosis Twin Inversion Genetic counselling |