Prenatal diagnosis of trisomy 9 mosaicism possibly limited to fetal membranes |
| |
| Authors: | Professor Dr R A Pfeiffer R Ulmer A Kniewald E Wagner-Thiessen |
| |
| Institution: | 1. Institut für Humangenetik der Friedrich-Alexander Universität Erlangen, Nürnberg, West Germany;2. Pothologisches Institut, der Friedrich-Alexander Universität Erlangen, Nürnberg, West Germany |
| |
| Abstract: | In repeat amniotic fluid cultures mosaicism due to trisomy 9 was noted. Autopsy of the aborted female fetus showed a sinus urogenitalis and gonadal dysgenesis with absence of germ cells only. Fetal lymphocytes and skin fibroblasts had a normal karyotype but trisomy 9 was found in cells grown from placenta. It is likely that trisomic cells were limited to fetal membranes. |
| |
| Keywords: | Prenatal cytogenetics Trisomy-9-mosaicism Chromosomal mosaicism limited to fetal membranes |
|
