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The acute toxicity of arsenobetaine
Authors:Toshikazu Kaise  Shigenobu Watanabe  Kazutoshi Itoh
Institution:Kanagawa Prefectual Public Health Laboratories Nakao-cho, Asahi-ku, Yokohama, 241, Japan
Abstract:The acute toxicity of arsenobetaine was studied in male mice. No deaths were observed with oral administration of 10 g/kg of arsenobetaine. Therefore the LD50 value was higher than 10 g/kg. This compound was found in urine in the non-metabolized form. No particular toxic symptoms were observed following administration. These results suggest that arsenobetaine has low toxicity and is not metabolized in mice.
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