Fetoscopic tracheal occlusion for treatment of non-isolated congenital diaphragmatic hernia |
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| Authors: | Viola Seravalli Eric B Jelin Jena L Miller Aylin Tekes Luca Vricella Ahmet A Baschat |
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| Institution: | 1. Center for Fetal Therapy, Department of Gynecology and Obstetrics, Johns Hopkins University School of Medicine, Baltimore, MD, USA;2. Department of Pediatric Surgery, Johns Hopkins Bloomberg Children's Center and Johns Hopkins University School of Medicine, Baltimore, MD, USA;3. Russell H. Morgan Department of Radiology and Radiological Science, Division of Pediatric Radiology and Pediatric Neuroradiology, Johns Hopkins University School of Medicine, Baltimore, MD, USA;4. Division of Cardiac Surgery, Johns Hopkins University School of Medicine, Baltimore, MD, USA |
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| Abstract: | Fetoscopic endotracheal occlusion (FETO) is a prenatal treatment that may increase survival in severe congenital diaphragmatic hernia (CDH). In the USA, FETO is offered for isolated severe left-sided CDH in the context of an FDA-approved feasibility study. FETO in non-isolated cases of severe CDH is only performed with a compassionate use exemption from US regulatory bodies. Anomalies frequently associated with CDH include congenital cystic lesions of the lung and cardiac defects. We describe two cases of non-isolated severe left-sided CDH that underwent prenatal FETO, survived after birth and underwent postnatal surgical repair. The potential benefit of FETO in this setting is discussed. © 2017 John Wiley & Sons, Ltd. |
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